Antioxidant and triglyceride-lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats. Antioxidants in Diabetes-Induced Complications (ADIC) Study Group

In this study, we evaluated the effects of vitamin E on the vascular reactivity and structure of thoracic aorta from streptozotocin (STZ)-diabetic rats. Plasma glucose, cholesterol, and triglyceride concentrations in rats were increased markedly by STZ-diabetes. The thiobarbituric acid (TBA) reactiv...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 1997-08, Vol.46 (8), p.872-879
Hauptverfasser:	Karasu, C, Ozansoy, G, Bozkurt, O, Erdoğan, D, Omeroğlu, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Aorta - drug effects Aorta - physiology Aortic Diseases - blood Aortic Diseases - etiology Aortic Diseases - metabolism Aortic Diseases - pathology Aortic Diseases - physiopathology Aortic Diseases - prevention & control Blood Glucose - drug effects Body Weight - drug effects Cholesterol - blood Diabetes Mellitus, Experimental - complications Diabetic Angiopathies - etiology Diabetic Angiopathies - prevention & control Dose-Response Relationship, Drug Endothelium, Vascular - drug effects Hypolipidemic Agents - therapeutic use Lipid Peroxidation - drug effects Male Nitroprusside - pharmacology Random Allocation Rats Triglycerides - blood Vasodilation - drug effects Vasodilator Agents - pharmacology Vitamin E - therapeutic use
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