Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules

A novel ATP-dependent export pump for amphiphilic anionic conjugates, which has been cloned recently from liver, was identified in rat kidney and localized to the apical membrane domain of proximal tubule epithelia. This 190-kD membrane glycoprotein (Mrp2) has been described previously as the hepato...

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Veröffentlicht in:Journal of the American Society of Nephrology 1997-08, Vol.8 (8), p.1213-1221
Hauptverfasser: SCHAUB, T. P, KARTENBECK, J, KÖNIG, J, VOGEL, O, WITZGALL, R, KRIZ, W, KEPPLER, D
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Sprache:eng
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