Kinetic and structural effects of activation of bovine kidney aldose reductase

Aldose reductase, purified to homogeneity from bovine kidney, is converted in a temperature-dependent process from a low-Km/low-Vmax form to a high-Km/high-Vmax form of the enzyme. Activation, which results in significant changes in the protein secondary structure, as detected by fluorescence spectr...

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Veröffentlicht in:Biochemistry (Easton) 1989-06, Vol.28 (13), p.5343-5353
Hauptverfasser: Grimshaw, C. E, Shahbaz, M, Jahangiri, G, Putney, C. G, McKercher, S. R, Mathur, E. J
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Sprache:eng
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