Differential cognitive effects of terfenadine and chlorpheniramine

The H 1-histamine antagonist, terfenadine, has been proposed to have reduced cognitive side effects. In the present study, the relative cognitive effects of terfenadine, 60 mg, chlorpheniramine maleate, 8 mg, and placebo were tested with a double-blind, randomized, three-period crossover design in 2...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1989-09, Vol.84 (3), p.322-325
Hauptverfasser:	Meador, Kimford J., Loring, David W., Thompson, Elaine E., Thompson, William O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Benzhydryl Compounds - pharmacology Biological and medical sciences Chlorpheniramine - pharmacology Cognition - drug effects Double-Blind Method Evoked Potentials, Somatosensory - drug effects Female Histamine and antagonists. Allergy Histamine H1 Antagonists - pharmacology Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Random Allocation Reaction Time - drug effects Terfenadine
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