$Structure and Specificity of a Class II MHC Alloreactive $\gamma \delta $ T Cell Receptor Heterodimer$

Structure and Specificity of a Class II MHC Alloreactive $\gamma \delta $ T Cell Receptor Heterodimer

Two distinct CD3-associated T cell receptors (TCR$\alpha \beta $ and TCR$\gamma \delta $) are expressed in a mutually exclusive fashion on separate subsets of T lymphocytes. While the specificity of the TCR$\alpha \beta $ repertoire for major histocompatibility complex (MHC) antigens is well establi...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1989-08, Vol.245 (4919), p.746-749
Hauptverfasser:	Matis, Louis A., Fry, Alicia M., Cron, Randy Q., Cotterman, Melissa M., Dick, Robert F., Bluestone, Jeffrey A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antibodies, Monoclonal Antigen receptors, T cell Antigens Antigens, Differentiation, T-Lymphocyte - analysis Antigens, Differentiation, T-Lymphocyte - immunology Antiserum Base Sequence CD3 Complex Cell Line Cell lines Cloning, Molecular Cytotoxicity, Immunologic H-2 Antigens - genetics H-2 Antigens - immunology Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology Hybridomas Hybridomas - immunology Immunosorbent Techniques Macromolecular Substances Major histocompatibility complex Messenger RNA Mice Mice, Nude Molecular Sequence Data Molecules Receptors Receptors, Antigen, T-Cell - analysis Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology T cell antigen receptors T cells T lymphocytes T-Lymphocytes - immunology
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