The Release and Detection of Endotoxin from Liposomes

Incorporation of lipopolysaccharide (LPS) into liposomes dramatically reduces its ability to coagulateLimulusamebocyte lysate (LAL). The coagulation of LAL is commonly used to signal the presence of endotoxinin vitro.This study demonstrates a simple method to release masked endotoxin from liposomal...

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Veröffentlicht in:	Analytical biochemistry 1997-08, Vol.250 (2), p.139-146
Hauptverfasser:	Harmon, Paul, Cabral-Lilly, Donna, Reed, Robert A., Maurio, Frank P., Franklin, J.Craig, Janoff, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Detergents - chemistry Detergents - pharmacology Drug Delivery Systems - methods Drug Monitoring - methods Endotoxins - chemistry Endotoxins - pharmacokinetics Horseshoe Crabs Liposomes - chemical synthesis Liposomes - chemistry
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