The potential for catheter microbial contamination from a needleless connector
Needleless connectors have been widely introduced into clinical practice to allow the connection of syringes and luers to peripheral and central vascular catheters. The potential for microbial contamination of catheters via these devices is currently unclear. A recently introduced connector, the ‘Co...
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| Veröffentlicht in: | The Journal of hospital infection 1997-07, Vol.36 (3), p.181-189 |
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| container_title | The Journal of hospital infection |
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| creator | Brown, J.D. Moss, H.A. Elliott, T.S.J. |
| description | Needleless connectors have been widely introduced into clinical practice to allow the connection of syringes and luers to peripheral and central vascular catheters. The potential for microbial contamination of catheters via these devices is currently unclear. A recently introduced connector, the ‘Connecta Clave’, was assessed by various in-vitro methods. The ‘Connecta Clave’ is specifically devised to separate external components from the fluid pathway. The compression seals of 50 devices were contaminated with 1 × 10
4 cfu
Staphylococcus epidermidis, disinfected with isopropanol, and fluid passed through. Only one device allowed organisms to pass through, despite this challenge, representing a contamination rate of 2%. In comparison, when 50 connectors were challenged with 20 cfu of
S. epidermidis, no organisms passed through the device during use. In the clinical situation, after manipulation, |
| doi_str_mv | 10.1016/S0195-6701(97)90193-6 |
| format | Article |
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4 cfu
Staphylococcus epidermidis, disinfected with isopropanol, and fluid passed through. Only one device allowed organisms to pass through, despite this challenge, representing a contamination rate of 2%. In comparison, when 50 connectors were challenged with 20 cfu of
S. epidermidis, no organisms passed through the device during use. In the clinical situation, after manipulation, <16 cfu of skin organisms were found associated with the compression seal of the devices. It is, therefore, likely that the contamination rates in clinical practice will be extremely low. Three methods of disinfecting the compression seals and associated rims were also evaluated. A combination of alcohol chlorhexidine spray, followed by a 70% isopropanol swab, resulted in the most efficacious disinfection. The isopropanol swabs produced an adequate disinfection rate. The overall results suggest that by use of specially designed connectors, not only are needlestick injuries reduced, but the likelihood of microbial contamination of catheters via the internal route may also be diminished.</description><identifier>ISSN: 0195-6701</identifier><identifier>EISSN: 1532-2939</identifier><identifier>DOI: 10.1016/S0195-6701(97)90193-6</identifier><identifier>PMID: 9253699</identifier><language>eng</language><publisher>Kent: Elsevier Ltd</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Catheters, Indwelling - microbiology ; Disinfection - methods ; Emergency and intensive care: techniques, logistics ; Equipment Contamination ; Filtration - instrumentation ; Humans ; Infusions, Intravenous - instrumentation ; Intensive care medicine ; Materials Testing ; Medical sciences ; Microbial contamination ; needleless connectors ; Needlestick Injuries - prevention & control ; Perfusions. Catheterizations. Hyperbaric oxygenotherapy ; S. epidermidis ; Skin - microbiology ; Staphylococcus epidermidis</subject><ispartof>The Journal of hospital infection, 1997-07, Vol.36 (3), p.181-189</ispartof><rights>1997</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c515t-5031675f6d40a24e9d6dd1767a826d107e51859e2bdd1a25b22d1419cf97ee63</citedby><cites>FETCH-LOGICAL-c515t-5031675f6d40a24e9d6dd1767a826d107e51859e2bdd1a25b22d1419cf97ee63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0195670197901936$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2746013$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9253699$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brown, J.D.</creatorcontrib><creatorcontrib>Moss, H.A.</creatorcontrib><creatorcontrib>Elliott, T.S.J.</creatorcontrib><title>The potential for catheter microbial contamination from a needleless connector</title><title>The Journal of hospital infection</title><addtitle>J Hosp Infect</addtitle><description>Needleless connectors have been widely introduced into clinical practice to allow the connection of syringes and luers to peripheral and central vascular catheters. The potential for microbial contamination of catheters via these devices is currently unclear. A recently introduced connector, the ‘Connecta Clave’, was assessed by various in-vitro methods. The ‘Connecta Clave’ is specifically devised to separate external components from the fluid pathway. The compression seals of 50 devices were contaminated with 1 × 10
4 cfu
Staphylococcus epidermidis, disinfected with isopropanol, and fluid passed through. Only one device allowed organisms to pass through, despite this challenge, representing a contamination rate of 2%. In comparison, when 50 connectors were challenged with 20 cfu of
S. epidermidis, no organisms passed through the device during use. In the clinical situation, after manipulation, <16 cfu of skin organisms were found associated with the compression seal of the devices. It is, therefore, likely that the contamination rates in clinical practice will be extremely low. Three methods of disinfecting the compression seals and associated rims were also evaluated. A combination of alcohol chlorhexidine spray, followed by a 70% isopropanol swab, resulted in the most efficacious disinfection. The isopropanol swabs produced an adequate disinfection rate. The overall results suggest that by use of specially designed connectors, not only are needlestick injuries reduced, but the likelihood of microbial contamination of catheters via the internal route may also be diminished.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Catheters, Indwelling - microbiology</subject><subject>Disinfection - methods</subject><subject>Emergency and intensive care: techniques, logistics</subject><subject>Equipment Contamination</subject><subject>Filtration - instrumentation</subject><subject>Humans</subject><subject>Infusions, Intravenous - instrumentation</subject><subject>Intensive care medicine</subject><subject>Materials Testing</subject><subject>Medical sciences</subject><subject>Microbial contamination</subject><subject>needleless connectors</subject><subject>Needlestick Injuries - prevention & control</subject><subject>Perfusions. Catheterizations. Hyperbaric oxygenotherapy</subject><subject>S. epidermidis</subject><subject>Skin - microbiology</subject><subject>Staphylococcus epidermidis</subject><issn>0195-6701</issn><issn>1532-2939</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1uGyEURlGUynF-HiHSLKqoWUzLZQYIq6qKmqRS1C7qPcJwRyGaAQdwpL59GdvyNivE9x3gcgi5BvoVKIhvfyko3gpJ4YuSt6ruulackCXwjrVMdeqULI_IGTnP-ZVSWnO-IAvFeCeUWpLfqxdsNrFgKN6MzRBTY015wYKpmbxNcT3HNoZiJh9M8TE0Q4pTY5qA6EYcMee5D2hLTJfk02DGjFeH9YKsHn6u7p_a5z-Pv-5_PLeWAy8tpx0IyQfhempYj8oJ50AKae6YcEAlcrjjCtm6xobxNWMOelB2UBJRdBfkZn_tJsW3LeaiJ58tjqMJGLdZSwWKUc4-BEH0veoYVJDvwfrlnBMOepP8ZNI_DVTPvvXOt55laiX1zreeJ7k-PLBdT-iOpw6Ca__50JtszTgkE6zPR4zJXlDoKvZ9j2GV9u4x6Ww9BovOpypWu-g_GOQ_HsGcIw</recordid><startdate>19970701</startdate><enddate>19970701</enddate><creator>Brown, J.D.</creator><creator>Moss, H.A.</creator><creator>Elliott, T.S.J.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T2</scope><scope>7U2</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19970701</creationdate><title>The potential for catheter microbial contamination from a needleless connector</title><author>Brown, J.D. ; Moss, H.A. ; Elliott, T.S.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c515t-5031675f6d40a24e9d6dd1767a826d107e51859e2bdd1a25b22d1419cf97ee63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Catheters, Indwelling - microbiology</topic><topic>Disinfection - methods</topic><topic>Emergency and intensive care: techniques, logistics</topic><topic>Equipment Contamination</topic><topic>Filtration - instrumentation</topic><topic>Humans</topic><topic>Infusions, Intravenous - instrumentation</topic><topic>Intensive care medicine</topic><topic>Materials Testing</topic><topic>Medical sciences</topic><topic>Microbial contamination</topic><topic>needleless connectors</topic><topic>Needlestick Injuries - prevention & control</topic><topic>Perfusions. Catheterizations. Hyperbaric oxygenotherapy</topic><topic>S. epidermidis</topic><topic>Skin - microbiology</topic><topic>Staphylococcus epidermidis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, J.D.</creatorcontrib><creatorcontrib>Moss, H.A.</creatorcontrib><creatorcontrib>Elliott, T.S.J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of hospital infection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, J.D.</au><au>Moss, H.A.</au><au>Elliott, T.S.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The potential for catheter microbial contamination from a needleless connector</atitle><jtitle>The Journal of hospital infection</jtitle><addtitle>J Hosp Infect</addtitle><date>1997-07-01</date><risdate>1997</risdate><volume>36</volume><issue>3</issue><spage>181</spage><epage>189</epage><pages>181-189</pages><issn>0195-6701</issn><eissn>1532-2939</eissn><abstract>Needleless connectors have been widely introduced into clinical practice to allow the connection of syringes and luers to peripheral and central vascular catheters. The potential for microbial contamination of catheters via these devices is currently unclear. A recently introduced connector, the ‘Connecta Clave’, was assessed by various in-vitro methods. The ‘Connecta Clave’ is specifically devised to separate external components from the fluid pathway. The compression seals of 50 devices were contaminated with 1 × 10
4 cfu
Staphylococcus epidermidis, disinfected with isopropanol, and fluid passed through. Only one device allowed organisms to pass through, despite this challenge, representing a contamination rate of 2%. In comparison, when 50 connectors were challenged with 20 cfu of
S. epidermidis, no organisms passed through the device during use. In the clinical situation, after manipulation, <16 cfu of skin organisms were found associated with the compression seal of the devices. It is, therefore, likely that the contamination rates in clinical practice will be extremely low. Three methods of disinfecting the compression seals and associated rims were also evaluated. A combination of alcohol chlorhexidine spray, followed by a 70% isopropanol swab, resulted in the most efficacious disinfection. The isopropanol swabs produced an adequate disinfection rate. The overall results suggest that by use of specially designed connectors, not only are needlestick injuries reduced, but the likelihood of microbial contamination of catheters via the internal route may also be diminished.</abstract><cop>Kent</cop><pub>Elsevier Ltd</pub><pmid>9253699</pmid><doi>10.1016/S0195-6701(97)90193-6</doi><tpages>9</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Catheters, Indwelling - microbiology Disinfection - methods Emergency and intensive care: techniques, logistics Equipment Contamination Filtration - instrumentation Humans Infusions, Intravenous - instrumentation Intensive care medicine Materials Testing Medical sciences Microbial contamination needleless connectors Needlestick Injuries - prevention & control Perfusions. Catheterizations. Hyperbaric oxygenotherapy S. epidermidis Skin - microbiology Staphylococcus epidermidis |
| title | The potential for catheter microbial contamination from a needleless connector |
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