An evaluation of 6 dentifrice formulations for supragingival anticalculus and antiplaque activity
A 4 week, double blind clinical trial was conducted to assess the antiplaque/anticalculus activity of test dentifrices containing varying levels of zinc citrate. Subjects were divided into 6 groups, 4 experimental, 1 positive control and a placebo group. All subjects only brushed at home using the p...
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| Veröffentlicht in: | Journal of clinical periodontology 1989-09, Vol.16 (8), p.525-528 |
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| container_end_page | 528 |
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| container_title | Journal of clinical periodontology |
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| creator | Disney, Judith A. Graves, Richard C. Cancro, Lewis Payonk, Gregory Stewart, Paul |
| description | A 4 week, double blind clinical trial was conducted to assess the antiplaque/anticalculus activity of test dentifrices containing varying levels of zinc citrate. Subjects were divided into 6 groups, 4 experimental, 1 positive control and a placebo group. All subjects only brushed at home using the placebo control during study weeks 1 and 3. Plaque and calculus were collected at the end of study weeks 2 and 4 on mylar strips worn on lower incisor teeth. Dentifrice efficacy was assessed by comparing group dry and ash weight decrements. While there were no significant differences between the test and control groups, there was a demonstrable trend toward greater inhibition with higher zinc citrate levels, expecially among subjects with high levels of plaque and calculus at baseline. |
| doi_str_mv | 10.1111/j.1600-051X.1989.tb02330.x |
| format | Article |
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Subjects were divided into 6 groups, 4 experimental, 1 positive control and a placebo group. All subjects only brushed at home using the placebo control during study weeks 1 and 3. Plaque and calculus were collected at the end of study weeks 2 and 4 on mylar strips worn on lower incisor teeth. Dentifrice efficacy was assessed by comparing group dry and ash weight decrements. While there were no significant differences between the test and control groups, there was a demonstrable trend toward greater inhibition with higher zinc citrate levels, expecially among subjects with high levels of plaque and calculus at baseline.</description><subject>Aluminum Oxide - therapeutic use</subject><subject>anticalculus formulation</subject><subject>Citrates - therapeutic use</subject><subject>Citric Acid</subject><subject>Clinical Trials as Topic</subject><subject>Dental Calculus - prevention & control</subject><subject>Dental Plaque - analysis</subject><subject>Dental Plaque - prevention & control</subject><subject>Dentifrices - therapeutic use</subject><subject>Dentistry</subject><subject>Double-Blind Method</subject><subject>Evaluation Studies as Topic</subject><subject>Fluorides - therapeutic use</subject><subject>Humans</subject><subject>Phosphates - therapeutic use</subject><subject>plaque inhibition</subject><subject>Regression Analysis</subject><subject>salts</subject><subject>Silicon Dioxide - therapeutic use</subject><subject>zinc</subject><subject>Zinc - therapeutic use</subject><subject>zinc citrate</subject><subject>zinc dentifrice</subject><subject>zinc mouthrinse</subject><issn>0303-6979</issn><issn>1600-051X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkFtLxDAQhYMoul5-glB88K110jRt44vIst7wCoK-hWmaStZsuyat7v57W3fZd0MgTM6cM8xHyAmFiPbnbBrRFCAETt8jKnIRtQXEjEG02CKjjbRNRsCAhanIxB7Z934KQDPG2C7ZjTkHHicjgpd1oL_Rdtiapg6aKkiDUtetqZxROqgaN-vsn-aHIvDd3OGHqT9Mbwqwb1RoVWc73xfl38fc4lenA1St-Tbt8pDsVGi9Plq_B-T1avI6vgnvn65vx5f3oUog5yFL4lJxLESGGYekAp2XMVRpzLgeLqZUVzkFLAosMqUFpKzgFJI8pzFwdkBOV7Fz1_TjfStnxittLda66bzMBBU05bRvPF81Ktd473Ql587M0C0lBTnglVM5MJQDQznglWu8ctGbj9dTumKmy411zbPXL1b6j7F6-Y9keTd-nvB42CNcJRjf6sUmAd2nTDOWcfn2eC1fhBiz5P1BJuwXjEWbUw</recordid><startdate>198909</startdate><enddate>198909</enddate><creator>Disney, Judith A.</creator><creator>Graves, Richard C.</creator><creator>Cancro, Lewis</creator><creator>Payonk, Gregory</creator><creator>Stewart, Paul</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198909</creationdate><title>An evaluation of 6 dentifrice formulations for supragingival anticalculus and antiplaque activity</title><author>Disney, Judith A. ; Graves, Richard C. ; Cancro, Lewis ; Payonk, Gregory ; Stewart, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4085-342dc5ab97a7504f0e8d20f6235e35e3a61ef810abbab7ce9063b51048812053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Aluminum Oxide - therapeutic use</topic><topic>anticalculus formulation</topic><topic>Citrates - therapeutic use</topic><topic>Citric Acid</topic><topic>Clinical Trials as Topic</topic><topic>Dental Calculus - prevention & control</topic><topic>Dental Plaque - analysis</topic><topic>Dental Plaque - prevention & control</topic><topic>Dentifrices - therapeutic use</topic><topic>Dentistry</topic><topic>Double-Blind Method</topic><topic>Evaluation Studies as Topic</topic><topic>Fluorides - therapeutic use</topic><topic>Humans</topic><topic>Phosphates - therapeutic use</topic><topic>plaque inhibition</topic><topic>Regression Analysis</topic><topic>salts</topic><topic>Silicon Dioxide - therapeutic use</topic><topic>zinc</topic><topic>Zinc - therapeutic use</topic><topic>zinc citrate</topic><topic>zinc dentifrice</topic><topic>zinc mouthrinse</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Disney, Judith A.</creatorcontrib><creatorcontrib>Graves, Richard C.</creatorcontrib><creatorcontrib>Cancro, Lewis</creatorcontrib><creatorcontrib>Payonk, Gregory</creatorcontrib><creatorcontrib>Stewart, Paul</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical periodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Disney, Judith A.</au><au>Graves, Richard C.</au><au>Cancro, Lewis</au><au>Payonk, Gregory</au><au>Stewart, Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An evaluation of 6 dentifrice formulations for supragingival anticalculus and antiplaque activity</atitle><jtitle>Journal of clinical periodontology</jtitle><addtitle>J Clin Periodontol</addtitle><date>1989-09</date><risdate>1989</risdate><volume>16</volume><issue>8</issue><spage>525</spage><epage>528</epage><pages>525-528</pages><issn>0303-6979</issn><eissn>1600-051X</eissn><abstract>A 4 week, double blind clinical trial was conducted to assess the antiplaque/anticalculus activity of test dentifrices containing varying levels of zinc citrate. Subjects were divided into 6 groups, 4 experimental, 1 positive control and a placebo group. All subjects only brushed at home using the placebo control during study weeks 1 and 3. Plaque and calculus were collected at the end of study weeks 2 and 4 on mylar strips worn on lower incisor teeth. Dentifrice efficacy was assessed by comparing group dry and ash weight decrements. While there were no significant differences between the test and control groups, there was a demonstrable trend toward greater inhibition with higher zinc citrate levels, expecially among subjects with high levels of plaque and calculus at baseline.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2550524</pmid><doi>10.1111/j.1600-051X.1989.tb02330.x</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0303-6979 |
| ispartof | Journal of clinical periodontology, 1989-09, Vol.16 (8), p.525-528 |
| issn | 0303-6979 1600-051X |
| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Aluminum Oxide - therapeutic use anticalculus formulation Citrates - therapeutic use Citric Acid Clinical Trials as Topic Dental Calculus - prevention & control Dental Plaque - analysis Dental Plaque - prevention & control Dentifrices - therapeutic use Dentistry Double-Blind Method Evaluation Studies as Topic Fluorides - therapeutic use Humans Phosphates - therapeutic use plaque inhibition Regression Analysis salts Silicon Dioxide - therapeutic use zinc Zinc - therapeutic use zinc citrate zinc dentifrice zinc mouthrinse |
| title | An evaluation of 6 dentifrice formulations for supragingival anticalculus and antiplaque activity |
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