Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer

BACKGROUND We recently isolated the KAI1 gene, a metastasis suppressor gene for prostate cancer, from human chromosome region 11p13–cen‐containing rat prostate cancer cells. The present study was performed to further locate the region of the KAI1 gene on the short arm of chromosome 11, and to examin...

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Veröffentlicht in:	The Prostate 1997-08, Vol.32 (3), p.205-213
Hauptverfasser:	Kawana, Youko, Komiya, Akira, Ueda, Takeshi, Nihei, Naoki, Kuramochi, Hiroaki, Suzuki, Hiroyoshi, Yatani, Ryuichi, Imai, Takashi, Dong, Jin-Tang, Imai, Toshio, Yoshie, Osamu, Barrett, J. Carl, Isaacs, John T., Shimazaki, Jun, Ito, Haruo, Ichikawa, Tomohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - pathology Alleles Animals Antigens, CD - genetics Autopsy Base Sequence Chromosome Mapping Chromosomes, Human, Pair 11 DNA Primers - analysis DNA Primers - chemistry DNA Primers - genetics DNA, Neoplasm - analysis DNA, Neoplasm - chemistry DNA, Neoplasm - genetics Gene Frequency Genes, Tumor Suppressor - genetics Heterozygote human chromosome 11 Humans Immunohistochemistry In Situ Hybridization, Fluorescence KAI1 Kangai-1 Protein loss of heterozygosity Male Membrane Glycoproteins - genetics metastasis suppressor gene Neoplasm Staging Polymerase Chain Reaction prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Proto-Oncogene Proteins Rats Tumor Cells, Cultured
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