HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas

The HER-2/neu gene codes for a membrane receptor protein that is homologous, but distinct from the epidermal growth factor receptor. This investigation was performed to validate fluorescence in situ hybridization (FISH) as a sensitive and specific method for assessing HER-2/neu gene amplification in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical oncology 1997-08, Vol.15 (8), p.2894-2904
Hauptverfasser:	PRESS, M. F, BERNSTEIN, L, SLAMON, D. J, PHILLIPS, R. N, ROSS, J. S, WOLMAN, S. R, FLOM, K. J, THOMAS, P. A, MEISNER, L. F, ZHOU, J.-Y, MA, Y, HUNG, G, ROBINSON, R. A, HARRIS, C, EL-NAGGAR, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Biomarkers, Tumor - genetics Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Female Gene Amplification Gynecology. Andrology. Obstetrics Humans Immunoblotting In Situ Hybridization, Fluorescence Lymphatic Metastasis Mammary gland diseases Medical sciences Middle Aged Neoplasm Metastasis Neoplasm Recurrence, Local Prognosis Receptor, ErbB-2 - genetics Sensitivity and Specificity Survival Rate Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!