Secretion of genetically engineered human/mouse class I antigens

Two soluble, secreted forms of HLA-B7 were engineered by the creation of hybrid human/mouse molecules containing the polymorphic 5′ region of the HLA-B7 gene and the secretory 3′ region of the mouse Q10 d gene. The hybrid, designated F1, is the first construct with only human extracytoplasmic domain...

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Veröffentlicht in:	Human immunology 1989-07, Vol.25 (3), p.207-222
Hauptverfasser:	Cohen, Nadine, Crawford, Jacqueline S., Hiraki, Debra D., Grumet, F.Carl
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Biological and medical sciences Biotechnology Cell Line Cell Separation Electrophoresis, Polyacrylamide Gel Enzyme-Linked Immunosorbent Assay Flow Cytometry Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Genetic engineering Genetic Engineering - methods Genetic technics Histocompatibility Antigens Class I - metabolism Humans Hybridomas - metabolism Methods. Procedures. Technologies Mice Precipitin Tests Transfection
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