Hepatitis B virus DNA forms in the liver of chronically infected individuals: Relation to replication profile

To analyze the profile of HBV-DNA forms in the liver in relation to different levels of virus replication, liver biopsies from 52 chronic HBsAg carriers were studied by Southern blot analysis. Quantitative evaluation of the major HBV-DNA molecules was carried out by densitometry in 27 patients with...

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Veröffentlicht in:	Journal of hepatology 1989-07, Vol.9 (1), p.29-35
Hauptverfasser:	Pontisso, P., Bortolotti, F., Fattovich, G., Ruvoletto, M.G., Realdi, G., Alberti, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Viral - analysis Biological and medical sciences Biopsy Blotting, Southern Chronic Disease DNA, Viral - biosynthesis DNA, Viral - blood DNA, Viral - genetics Hepatitis B - metabolism Hepatitis B e Antigens - analysis Hepatitis B Surface Antigens - analysis Hepatitis B virus - genetics Hepatitis B virus - immunology Human viral diseases Humans Infectious diseases Liver - metabolism Medical sciences Nucleic Acid Hybridization Viral diseases Viral hepatitis Virus Replication
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