Expression and splicing of the fibronectin gene in healthy and diseased periodontal tissue

Fibronectin is a major component of the extracellular matrix and is considered to have an important role in chronic inflammatory periodontal disease. The fibronectin gene product has been shown to be subject to alternative splicing in 3 regions, each generating different mRNA transcripts associated...

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Veröffentlicht in:	European journal of oral sciences 1997-06, Vol.105 (3), p.264-270
Hauptverfasser:	Parkar, Mohamed H., Bakalios, Panagiotis, Newman, Hubert N., Olsen, Irwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alternative Splicing - genetics Antigens - genetics Antigens - physiology Cells, Cultured Chronic Disease Culture Techniques Dentistry Down-Regulation - genetics Embryonic and Fetal Development - genetics Exons - genetics Extracellular Matrix - metabolism fibronectin Fibronectins - genetics Fibronectins - immunology Fibronectins - metabolism Gene Expression Regulation - genetics Gene Expression Regulation, Developmental - genetics Humans Inflammation Mediators - metabolism Insulin-Like Growth Factor I - genetics Interleukin-1 - genetics Molecular Weight periodontal disease Periodontitis - genetics Periodontitis - metabolism Periodontium - metabolism Platelet-Derived Growth Factor - genetics Polymerase Chain Reaction Regeneration - genetics RNA, Messenger - genetics splicing Transcription, Genetic Transforming Growth Factor beta - genetics Up-Regulation - genetics Wound Healing - genetics
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