Prognostic factors in mobile tongue and floor of mouth carcinoma
This study identifies significant prognostic factors in squamous cell carcinomas of the anterior tongue and floor of mouth. It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and...
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| Veröffentlicht in: | Cancer 1989-09, Vol.64 (6), p.1195-1202 |
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| container_title | Cancer |
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| creator | Brown, Bert Barnes, Leon Mazariegos, Juan Taylor, Floyd Johnson, Jonas Wagner, Robin L. |
| description | This study identifies significant prognostic factors in squamous cell carcinomas of the anterior tongue and floor of mouth. It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and intralymphatic tumor emboli should be examined in all resected tumors. Tumor thickness, tumor size, and perineural invasion all have an impact on survival and must be considered in treatment plans. Tumors measuring between 2 mm and 3 mm may or may not have metastases and further evaluation of this group needs to be done. Most importantly, the data in this study supports a multiinstitutional prospective evaluation of pathology specimens. Precise guidelines must be established for handling of the specimen, which must then be evaluated for the variables mentioned above. In this way, more definitive conclusions can be reached in the management of tumors of the antierior tongue and floor of mouth. |
| doi_str_mv | 10.1002/1097-0142(19890915)64:6<1195::AID-CNCR2820640606>3.0.CO;2-7 |
| format | Article |
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It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and intralymphatic tumor emboli should be examined in all resected tumors. Tumor thickness, tumor size, and perineural invasion all have an impact on survival and must be considered in treatment plans. Tumors measuring between 2 mm and 3 mm may or may not have metastases and further evaluation of this group needs to be done. Most importantly, the data in this study supports a multiinstitutional prospective evaluation of pathology specimens. Precise guidelines must be established for handling of the specimen, which must then be evaluated for the variables mentioned above. In this way, more definitive conclusions can be reached in the management of tumors of the antierior tongue and floor of mouth.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19890915)64:6<1195::AID-CNCR2820640606>3.0.CO;2-7</identifier><identifier>PMID: 2766218</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Aged ; Biological and medical sciences ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - secondary ; Female ; Follow-Up Studies ; Humans ; Lymphatic Metastasis ; Male ; Medical sciences ; Middle Aged ; Mouth Floor ; Mouth Neoplasms - mortality ; Mouth Neoplasms - pathology ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Neoplastic Cells, Circulating ; Otorhinolaryngology. Stomatology ; Prognosis ; Retrospective Studies ; Tongue Neoplasms - mortality ; Tongue Neoplasms - pathology ; Tumors ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Cancer, 1989-09, Vol.64 (6), p.1195-1202</ispartof><rights>Copyright © 1989 American Cancer Society</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5656-e04088aedede0599c30ddecb22d9bae52930c49474940373de6f7c28b2885dd93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19409399$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2766218$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brown, Bert</creatorcontrib><creatorcontrib>Barnes, Leon</creatorcontrib><creatorcontrib>Mazariegos, Juan</creatorcontrib><creatorcontrib>Taylor, Floyd</creatorcontrib><creatorcontrib>Johnson, Jonas</creatorcontrib><creatorcontrib>Wagner, Robin L.</creatorcontrib><title>Prognostic factors in mobile tongue and floor of mouth carcinoma</title><title>Cancer</title><addtitle>Cancer</addtitle><description>This study identifies significant prognostic factors in squamous cell carcinomas of the anterior tongue and floor of mouth. It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and intralymphatic tumor emboli should be examined in all resected tumors. Tumor thickness, tumor size, and perineural invasion all have an impact on survival and must be considered in treatment plans. Tumors measuring between 2 mm and 3 mm may or may not have metastases and further evaluation of this group needs to be done. Most importantly, the data in this study supports a multiinstitutional prospective evaluation of pathology specimens. Precise guidelines must be established for handling of the specimen, which must then be evaluated for the variables mentioned above. In this way, more definitive conclusions can be reached in the management of tumors of the antierior tongue and floor of mouth.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mouth Floor</subject><subject>Mouth Neoplasms - mortality</subject><subject>Mouth Neoplasms - pathology</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neoplasm Staging</subject><subject>Neoplastic Cells, Circulating</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Tongue Neoplasms - mortality</subject><subject>Tongue Neoplasms - pathology</subject><subject>Tumors</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkG9r1TAUxoMo8276EYS-UbYXvTtJ2vy5ijiqzsHwiigIvjikaTorbbMlLbJvb8q9TvSFICGEw3Py8Dw_QioKawrATilomQMt2DHVSoOm5YkoNuIFpbrcbM4uXufV--ojUwxEAQLES76GdbV9znJ5j6zuft8nKwBQeVnwLw_JYYzf0yhZyQ_IAZNCMKpW5NWH4K9GH6fOZq2xkw8x68Zs8HXXu2zy49XsMjM2Wdt7HzLfJmmevmXWBNuNfjCPyIPW9NE93r9H5PPbN5-qd_nl9vyiOrvMbSlKkTsoQCnjmnSg1NpyaBpna8YaXRtXMs3BFrqQ6QKXvHGilZapmilVNo3mR-TZzvc6-JvZxQmHLlrX92Z0fo4oNZU0VUqLX3eLNvgYg2vxOnSDCbdIARe-uBDChRD-4ouiQIELX8TEF__kixwBqy0ylMn9yT7GXA-uufPeA036071uojV9G8xou_g7QmqnuV7qtLu9H4nz7f9F_GfCvxT-E3IHpF8</recordid><startdate>19890915</startdate><enddate>19890915</enddate><creator>Brown, Bert</creator><creator>Barnes, Leon</creator><creator>Mazariegos, Juan</creator><creator>Taylor, Floyd</creator><creator>Johnson, Jonas</creator><creator>Wagner, Robin L.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19890915</creationdate><title>Prognostic factors in mobile tongue and floor of mouth carcinoma</title><author>Brown, Bert ; Barnes, Leon ; Mazariegos, Juan ; Taylor, Floyd ; Johnson, Jonas ; Wagner, Robin L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5656-e04088aedede0599c30ddecb22d9bae52930c49474940373de6f7c28b2885dd93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - secondary</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mouth Floor</topic><topic>Mouth Neoplasms - mortality</topic><topic>Mouth Neoplasms - pathology</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Recurrence, Local</topic><topic>Neoplasm Staging</topic><topic>Neoplastic Cells, Circulating</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Tongue Neoplasms - mortality</topic><topic>Tongue Neoplasms - pathology</topic><topic>Tumors</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, Bert</creatorcontrib><creatorcontrib>Barnes, Leon</creatorcontrib><creatorcontrib>Mazariegos, Juan</creatorcontrib><creatorcontrib>Taylor, Floyd</creatorcontrib><creatorcontrib>Johnson, Jonas</creatorcontrib><creatorcontrib>Wagner, Robin L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, Bert</au><au>Barnes, Leon</au><au>Mazariegos, Juan</au><au>Taylor, Floyd</au><au>Johnson, Jonas</au><au>Wagner, Robin L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic factors in mobile tongue and floor of mouth carcinoma</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1989-09-15</date><risdate>1989</risdate><volume>64</volume><issue>6</issue><spage>1195</spage><epage>1202</epage><pages>1195-1202</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>This study identifies significant prognostic factors in squamous cell carcinomas of the anterior tongue and floor of mouth. It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and intralymphatic tumor emboli should be examined in all resected tumors. Tumor thickness, tumor size, and perineural invasion all have an impact on survival and must be considered in treatment plans. Tumors measuring between 2 mm and 3 mm may or may not have metastases and further evaluation of this group needs to be done. Most importantly, the data in this study supports a multiinstitutional prospective evaluation of pathology specimens. Precise guidelines must be established for handling of the specimen, which must then be evaluated for the variables mentioned above. In this way, more definitive conclusions can be reached in the management of tumors of the antierior tongue and floor of mouth.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2766218</pmid><doi>10.1002/1097-0142(19890915)64:6<1195::AID-CNCR2820640606>3.0.CO;2-7</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Aged Biological and medical sciences Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - secondary Female Follow-Up Studies Humans Lymphatic Metastasis Male Medical sciences Middle Aged Mouth Floor Mouth Neoplasms - mortality Mouth Neoplasms - pathology Neoplasm Invasiveness Neoplasm Recurrence, Local Neoplasm Staging Neoplastic Cells, Circulating Otorhinolaryngology. Stomatology Prognosis Retrospective Studies Tongue Neoplasms - mortality Tongue Neoplasms - pathology Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | Prognostic factors in mobile tongue and floor of mouth carcinoma |
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