Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: Implications for hyperpolarized xenon MRI
Subjective and physiologic effects of 33% inhaled Xe were measured with 15O‐water positron emission tomography (PET) in 3 subjects at rest and during visual stimulation. The procedure was well tolerated. Robust functional activations of the visual cortex were obtained after xenon (Xe) inhalation as...
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| Veröffentlicht in: | Journal of magnetic resonance imaging 1997-07, Vol.7 (4), p.761-764 |
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| container_end_page | 764 |
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| container_issue | 4 |
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| container_title | Journal of magnetic resonance imaging |
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| creator | Liotti, Mario Martin, Charles C. Gao, Jia-Hong Roby, John W. Mayberg, Helen S. Zamarripa, Frank Jerabek, Paul A. Fox, Peter T. |
| description | Subjective and physiologic effects of 33% inhaled Xe were measured with 15O‐water positron emission tomography (PET) in 3 subjects at rest and during visual stimulation. The procedure was well tolerated. Robust functional activations of the visual cortex were obtained after xenon (Xe) inhalation as well as air breathing. However, Xe inhalation was followed by smaller size, but significant decreases of regional cerebral blood flow (rCBF) in visual cortex relative to the air‐breathing baseline, both during visual stimulation and at rest. No such decreases were found in other sensory or motor regions. |
| doi_str_mv | 10.1002/jmri.1880070424 |
| format | Article |
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No such decreases were found in other sensory or motor regions.</description><subject>Adult</subject><subject>Brain - diagnostic imaging</subject><subject>Cerebrovascular Circulation - drug effects</subject><subject>Depression, Chemical</subject><subject>Humans</subject><subject>Hyperpolarized Xe-MRI</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Oxygen Radioisotopes</subject><subject>Photic Stimulation</subject><subject>Positron emission tomography</subject><subject>Tomography, Emission-Computed</subject><subject>Visual Cortex - blood supply</subject><subject>Visual Cortex - drug effects</subject><subject>Visual Cortex - physiology</subject><subject>Water</subject><subject>Xenon</subject><subject>Xenon - administration & dosage</subject><subject>Xenon - pharmacology</subject><issn>1053-1807</issn><issn>1522-2586</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUdFOHCEUJaaNVetzn5rw1LdR7gAL0z7VTdVt1U2aNvaNMLN3FMssU5iNjn_gX8t2N5qQcODcc-DeQ8gHYEfAWHl810V3BFozppgoxQ7ZA1mWRSn15E3GTPICNFPvyH5Kd4yxqhJyl-xWpeC8qvbI0x9chiXFtsVmSDTDiDcuLK2nDUasYwa1D2FBWx_uqU0J81rQeqQg58V5Oad9SG6Ia5POpZS1dAhduIm2vx0_01nXe9fYId8n2oZIb8ceYx-8je4xGz38f__y5-w9edtan_Bwux-Q36fffk3Pi4v52Wz69aJwILjI3TSoeF0rq4RWgO2iAd5KkICohbJQA1c1160uJeYpgEWUnKMVAiomJD8gnza-fQz_VpgGk7_doPd2iWGVjKpgooUUufDjtnBVd7gwfXSdjaPZzi7zXzb8vfM4vtDAzDoZs07GvCZjvuceX49ZXWzULg348KK28a-ZKK6kub46M-J6-kMILs0JfwYHo5Mx</recordid><startdate>199707</startdate><enddate>199707</enddate><creator>Liotti, Mario</creator><creator>Martin, Charles C.</creator><creator>Gao, Jia-Hong</creator><creator>Roby, John W.</creator><creator>Mayberg, Helen S.</creator><creator>Zamarripa, Frank</creator><creator>Jerabek, Paul A.</creator><creator>Fox, Peter T.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199707</creationdate><title>Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: Implications for hyperpolarized xenon MRI</title><author>Liotti, Mario ; Martin, Charles C. ; Gao, Jia-Hong ; Roby, John W. ; Mayberg, Helen S. ; Zamarripa, Frank ; Jerabek, Paul A. ; Fox, Peter T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i1434-18ce73bb7a74871efdc13f5151ee847a1b137b38f825e5861aee533ea44190453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Brain - diagnostic imaging</topic><topic>Cerebrovascular Circulation - drug effects</topic><topic>Depression, Chemical</topic><topic>Humans</topic><topic>Hyperpolarized Xe-MRI</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Oxygen Radioisotopes</topic><topic>Photic Stimulation</topic><topic>Positron emission tomography</topic><topic>Tomography, Emission-Computed</topic><topic>Visual Cortex - blood supply</topic><topic>Visual Cortex - drug effects</topic><topic>Visual Cortex - physiology</topic><topic>Water</topic><topic>Xenon</topic><topic>Xenon - administration & dosage</topic><topic>Xenon - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liotti, Mario</creatorcontrib><creatorcontrib>Martin, Charles C.</creatorcontrib><creatorcontrib>Gao, Jia-Hong</creatorcontrib><creatorcontrib>Roby, John W.</creatorcontrib><creatorcontrib>Mayberg, Helen S.</creatorcontrib><creatorcontrib>Zamarripa, Frank</creatorcontrib><creatorcontrib>Jerabek, Paul A.</creatorcontrib><creatorcontrib>Fox, Peter T.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liotti, Mario</au><au>Martin, Charles C.</au><au>Gao, Jia-Hong</au><au>Roby, John W.</au><au>Mayberg, Helen S.</au><au>Zamarripa, Frank</au><au>Jerabek, Paul A.</au><au>Fox, Peter T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: Implications for hyperpolarized xenon MRI</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J. Magn. Reson. Imaging</addtitle><date>1997-07</date><risdate>1997</risdate><volume>7</volume><issue>4</issue><spage>761</spage><epage>764</epage><pages>761-764</pages><issn>1053-1807</issn><eissn>1522-2586</eissn><abstract>Subjective and physiologic effects of 33% inhaled Xe were measured with 15O‐water positron emission tomography (PET) in 3 subjects at rest and during visual stimulation. The procedure was well tolerated. Robust functional activations of the visual cortex were obtained after xenon (Xe) inhalation as well as air breathing. However, Xe inhalation was followed by smaller size, but significant decreases of regional cerebral blood flow (rCBF) in visual cortex relative to the air‐breathing baseline, both during visual stimulation and at rest. No such decreases were found in other sensory or motor regions.</abstract><cop>Baltimore</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>9243399</pmid><doi>10.1002/jmri.1880070424</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1053-1807 |
| ispartof | Journal of magnetic resonance imaging, 1997-07, Vol.7 (4), p.761-764 |
| issn | 1053-1807 1522-2586 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Brain - diagnostic imaging Cerebrovascular Circulation - drug effects Depression, Chemical Humans Hyperpolarized Xe-MRI Magnetic Resonance Imaging - methods Male Oxygen Radioisotopes Photic Stimulation Positron emission tomography Tomography, Emission-Computed Visual Cortex - blood supply Visual Cortex - drug effects Visual Cortex - physiology Water Xenon Xenon - administration & dosage Xenon - pharmacology |
| title | Xenon effects on regional cerebral blood flow assessed by 15O-H2O positron emission tomography: Implications for hyperpolarized xenon MRI |
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