Synthesis, Uptake, and Intracellular Metabolism of a Hydrophobic Tetrapeptide-Peptide Nucleic Acid (PNA)–Biotin Molecule

Peptide nucleic acid (PNA) molecules are very promising tools for antigene and antisense therapies because of their remarkable refractoriness to degradation in biological fluids. However, very limited information is available on their uptake by potentially target cells and on their intracellular fat...

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Veröffentlicht in:	Biochemical and biophysical research communications 1997-07, Vol.236 (2), p.323-326
Hauptverfasser:	Scarfı́, Sonia, Gasparini, Anna, Damonte, Gianluca, Benatti, Umberto
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes Biological Transport Cell Membrane Permeability Cells, Cultured Erythrocytes Humans Oligonucleotides - chemistry Oligopeptides - chemistry Oligopeptides - metabolism Solubility
Online-Zugang:	Volltext
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