Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH: homology to human cyclin-dependent kinase activating kinase and IIH subunits

Genes for the Tfb2, Tfb3, and Tfb4 subunits of yeast RNA polymerase transcription factor IIH (TFIIH) are described. All three genes are essential for cell viability, and antibodies against Tfb3 specifically inhibit transcription in vitro. A C-terminal deletion of Tfb2 caused a defect in nucleotide e...

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Veröffentlicht in:	The Journal of biological chemistry 1997-08, Vol.272 (31), p.19319-19327
Hauptverfasser:	Feaver, W.J. (Stanford University School of Medicine, Stanford, CA.), Henry, N.L, Wang, Z, Wu, X, Svejstrup, J.Q, Bushnell, D.A, Friedberg, E.C, Kornberg, R.D
Format:	Artikel
Sprache:	eng
Schlagworte:	ADN Amino Acid Sequence AMINO ACID SEQUENCES ANTIBODIES ANTICORPS ANTICUERPOS Base Sequence Cell Survival CHEMICAL COMPOSITION COMPARISONS COMPLEMENTATION COMPOSICION QUIMICA COMPOSITION CHIMIQUE Cyclin-Dependent Kinases - metabolism DELETIONS DNA DNA REPAIR FACTEUR DE TRANSCRIPTION FACTORES DE TRANSCRIPCION GENBANK/U62804 GENBANK/U62805 GENE GENERO HUMANO GENES GENETICA GENETICS GENETIQUE GENRE HUMAIN Humans INHIBICION INHIBITION MANKIND MOLECULAR SEQUENCE DATA MUTANT MUTANTES MUTANTS NUCLEOTIDE EXCISION REPAIR NUCLEOTIDE SEQUENCE OPEN READING FRAMES PROTEIN KINASE PROTEINA QUINASA PROTEINE KINASE SACCHAROMYCES CEREVISIAE SECUENCIA NUCLEOTIDICA Sequence Homology, Amino Acid SEQUENCE NUCLEOTIDIQUE STRUCTURAL GENES TFB2 GENE TFB3 GENE TRANSCRIPCION TRANSCRIPTION Transcription Factor TFIIH TRANSCRIPTION FACTORS Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors, TFII VIABILIDAD VIABILITE VIABILITY
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