Selective usage of defined TCRBV genes in response to filarial antigens

The characterization of T cell reactivities that are prone to down-modulation by filarial parasites is central to understanding how these nematodes can survive for long periods of time within their human host and to design appropriate immunoprophylactic measures. In the present study, TCRBV gene usa...

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Veröffentlicht in:	International immunology 1997-07, Vol.9 (7), p.955-962
Hauptverfasser:	Sartono, E, van Eggermond, M C, Kurniawan, A, Maizels, R M, van den Elsen, P J, Yazdanbakhsh, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Antigens, Helminth - immunology Brugia malayi Brugia malayi - growth & development Brugia malayi - immunology Clone Cells - metabolism Diethylcarbamazine - pharmacology Elephantiasis, Filarial - genetics Elephantiasis, Filarial - immunology Female Gene Rearrangement, beta-Chain T-Cell Antigen Receptor - drug effects Humans Lymphocyte Activation - genetics Male Middle Aged Multigene Family - drug effects Multigene Family - immunology Polymerase Chain Reaction Receptors, Antigen, T-Cell, alpha-beta - drug effects Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, alpha-beta - immunology T-Lymphocyte Subsets - metabolism
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