Uptake of γ-aminobutyric acid and l-glutamic acid by synaptosomes from postmortem human cerebral cortex: multiple sites, sodium dependence and effect of tissue preparation

The uptake of γ-aminobutyric acid (GABA) and l-glutamic acid by synaptosomes prepared from frozen postmortem human brain was shown to be affected via distinct high and low affinity sites. At approximately 17 h postmortem delay, the kinetic parameters for GABA uptake were: high affinity site, K m 7.1...

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