Immunoregulatory activity in supernatants from cultures of normal human trophoblast cells of the first trimester

Supernatants from isolated trophoblast cell cultures (trophoblastic fluid) derived from first-trimester human placentas were assessed for immunoregulatory activity. Trophoblastic fluid at different days of culture consistently inhibited the blast transformation of allogenic lymphocytes. This suppres...

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Veröffentlicht in:	American journal of obstetrics and gynecology 1989-08, Vol.161 (2), p.446-453
Hauptverfasser:	Sanyal, Mrinal K., Brami, Charles J., Bischof, Paul, Simmons, Edwina, Barnea, Eytan R., Dwyer, John M., Naftolin, Frederick
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cells, Cultured Chorionic Gonadotropin - analysis Chorionic Gonadotropin, beta Subunit, Human Embryology: invertebrates and vertebrates. Teratology Female first trimester Fundamental and applied biological sciences. Psychology General aspects. Development. Fetal membranes Humans Immune Tolerance Immunity, Cellular immunosuppression Leukocytes, Mononuclear - immunology Peptide Fragments - analysis Pregnancy Pregnancy Trimester, First Pregnancy-associated plasma protein A Pregnancy-Associated Plasma Protein-A - analysis Reference Values suppressor cell activation T-Lymphocytes, Regulatory - immunology trophoblast cell culture Trophoblasts - analysis Trophoblasts - immunology
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