Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles

Electron microscope immunocytochemistry reveals that both anterograde-directed (proinsulin and VSV G protein) and retrograde-directed (the KDEL receptor) cargo are present in COPI-coated vesicles budding from every level of the Golgi stack in whole cells; however, they comprise two distinct populati...

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Veröffentlicht in:	Cell 1997-07, Vol.90 (2), p.335-349
Hauptverfasser:	Orci, Lelio, Stamnes, Mark, Ravazzola, Mariella, Amherdt, Mylène, Perrelet, Alain, Söllner, Thomas H, Rothman, James E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological Transport - physiology Cell-Free System Cells, Cultured Coated Vesicles - chemistry Coated Vesicles - metabolism Coated Vesicles - ultrastructure Coatomer Protein Golgi Apparatus - chemistry Golgi Apparatus - metabolism Golgi Apparatus - ultrastructure Membrane Proteins - analysis Membrane Proteins - metabolism Microscopy, Immunoelectron Pancreas - cytology Rats Receptors, Peptide - analysis vesicular stomatitis virus
Online-Zugang:	Volltext
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