Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1

Several reports have demonstrated that cerebral blood flow decreases with age and may contribute to neurodegenerative changes found in aging animals and man. Because GH and insulin-like growth factor 1 (IGF-1) decrease with age and have an important role in vascular maintenance and remodeling, we hy...

Ausführliche Beschreibung