Silicone rubber-hydrogel composites as polymeric biomaterials: IX. Composites containing powdery polyacrylamide hydrogel
A composite material has been prepared consisting of a silicone rubber matrix and particulate lightly cross-linked polyacrylamide hydrogel. The material, resembling common silicone rubber, is hydrophilic and swells in water like hydrogels. The polyacrylamide has a high specific surface area, a relat...
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| Veröffentlicht in: | Biomaterials 1997-08, Vol.18 (15), p.1069-1073 |
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| container_title | Biomaterials |
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| creator | Hron, P. Šlechtová, J. Smetana, K. Dvořánková, B. Lopour, P. |
| description | A composite material has been prepared consisting of a silicone rubber matrix and particulate lightly cross-linked polyacrylamide hydrogel. The material, resembling common silicone rubber, is hydrophilic and swells in water like hydrogels. The polyacrylamide has a high specific surface area, a relatively low content of water-soluble low-molecular-weight compounds and, owing to its nonionogenic character, a pH-independent swelling degree. For the composite material consisting of the silicone rubber and very fine powdery cross-linked polyacrylamide, we have measured the rate of swelling in water, the mechanical properties (tensile strength, break elongation, hardness, resilience), biological properties (implantation test, cytotoxicity, cell cultivation) and UV absorption of its water extracts. The polyacrylamide and polysiloxane purity, as the composite material starting components, has been determined to be satisfactory. As a result, a high swelling rate of the prepared composite material has been observed, resulting in reaching more than 70% wt of water of the equilibrium swelling. The results show that the composite material is suitable for biological and medical use. |
| doi_str_mv | 10.1016/S0142-9612(97)00039-2 |
| format | Article |
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Composites containing powdery polyacrylamide hydrogel</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Hron, P. ; Šlechtová, J. ; Smetana, K. ; Dvořánková, B. ; Lopour, P.</creator><creatorcontrib>Hron, P. ; Šlechtová, J. ; Smetana, K. ; Dvořánková, B. ; Lopour, P.</creatorcontrib><description>A composite material has been prepared consisting of a silicone rubber matrix and particulate lightly cross-linked polyacrylamide hydrogel. The material, resembling common silicone rubber, is hydrophilic and swells in water like hydrogels. The polyacrylamide has a high specific surface area, a relatively low content of water-soluble low-molecular-weight compounds and, owing to its nonionogenic character, a pH-independent swelling degree. For the composite material consisting of the silicone rubber and very fine powdery cross-linked polyacrylamide, we have measured the rate of swelling in water, the mechanical properties (tensile strength, break elongation, hardness, resilience), biological properties (implantation test, cytotoxicity, cell cultivation) and UV absorption of its water extracts. The polyacrylamide and polysiloxane purity, as the composite material starting components, has been determined to be satisfactory. As a result, a high swelling rate of the prepared composite material has been observed, resulting in reaching more than 70% wt of water of the equilibrium swelling. The results show that the composite material is suitable for biological and medical use.</description><identifier>ISSN: 0142-9612</identifier><identifier>EISSN: 1878-5905</identifier><identifier>DOI: 10.1016/S0142-9612(97)00039-2</identifier><identifier>PMID: 9239469</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>3T3 Cells ; Acrylic Resins - chemistry ; Animals ; Biocompatible Materials ; Biological and medical sciences ; Cell Adhesion ; composite ; Composite Resins - chemistry ; Humans ; hydrogel ; Keratinocytes ; Materials Testing ; Medical sciences ; Mice ; Polyacrylamide ; Polymers - chemistry ; Powders ; Prostheses and Implants ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Rats ; Rats, Wistar ; silicone rubber ; Silicones - chemistry ; Spectrophotometry, Ultraviolet ; Technology. Biomaterials. Equipments. Material. Instrumentation ; Tensile Strength ; Tetrazolium Salts ; Thiazoles ; Water</subject><ispartof>Biomaterials, 1997-08, Vol.18 (15), p.1069-1073</ispartof><rights>1997</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-7a7fbf543071d0e3fcdba0532e3e57747de78a42554ca08bd8de82c7cfa754053</citedby><cites>FETCH-LOGICAL-c335t-7a7fbf543071d0e3fcdba0532e3e57747de78a42554ca08bd8de82c7cfa754053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0142-9612(97)00039-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2738873$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9239469$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hron, P.</creatorcontrib><creatorcontrib>Šlechtová, J.</creatorcontrib><creatorcontrib>Smetana, K.</creatorcontrib><creatorcontrib>Dvořánková, B.</creatorcontrib><creatorcontrib>Lopour, P.</creatorcontrib><title>Silicone rubber-hydrogel composites as polymeric biomaterials: IX. Composites containing powdery polyacrylamide hydrogel</title><title>Biomaterials</title><addtitle>Biomaterials</addtitle><description>A composite material has been prepared consisting of a silicone rubber matrix and particulate lightly cross-linked polyacrylamide hydrogel. The material, resembling common silicone rubber, is hydrophilic and swells in water like hydrogels. The polyacrylamide has a high specific surface area, a relatively low content of water-soluble low-molecular-weight compounds and, owing to its nonionogenic character, a pH-independent swelling degree. For the composite material consisting of the silicone rubber and very fine powdery cross-linked polyacrylamide, we have measured the rate of swelling in water, the mechanical properties (tensile strength, break elongation, hardness, resilience), biological properties (implantation test, cytotoxicity, cell cultivation) and UV absorption of its water extracts. The polyacrylamide and polysiloxane purity, as the composite material starting components, has been determined to be satisfactory. As a result, a high swelling rate of the prepared composite material has been observed, resulting in reaching more than 70% wt of water of the equilibrium swelling. The results show that the composite material is suitable for biological and medical use.</description><subject>3T3 Cells</subject><subject>Acrylic Resins - chemistry</subject><subject>Animals</subject><subject>Biocompatible Materials</subject><subject>Biological and medical sciences</subject><subject>Cell Adhesion</subject><subject>composite</subject><subject>Composite Resins - chemistry</subject><subject>Humans</subject><subject>hydrogel</subject><subject>Keratinocytes</subject><subject>Materials Testing</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Polyacrylamide</subject><subject>Polymers - chemistry</subject><subject>Powders</subject><subject>Prostheses and Implants</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>silicone rubber</subject><subject>Silicones - chemistry</subject><subject>Spectrophotometry, Ultraviolet</subject><subject>Technology. Biomaterials. Equipments. Material. Instrumentation</subject><subject>Tensile Strength</subject><subject>Tetrazolium Salts</subject><subject>Thiazoles</subject><subject>Water</subject><issn>0142-9612</issn><issn>1878-5905</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1O3DAUhS1URKeUR0DKoqroIuDf2O6mQqO2ICGxoEjsLMe-oa6SeGpn2ubtMTPTYcnKtu53zrXOQeiU4HOCSXNxhwmntW4IPdPyE8aY6ZoeoAVRUtVCY_EGLfbIW_Qu51-4vDGnR-hIU6Z5oxfo313og4sjVGndtpDqn7NP8RH6ysVhFXOYIFc2V6vYzwOk4Ko2xMFO5Wr7_Lm6fjivli9kcZpsGMP4WBR_PaR5o7Quzb0dgofqv_97dNgVBzjZncfo_tvXH8ur-ub2-_Xy8qZ2jImpllZ2bSc4w5J4DKxzvrVYMAoMhJRcepDKcioEdxar1isPijrpOisFL-Ax-rj1XaX4ew15MkPIDvrejhDX2UhNuG548ypISoxUUVlAsQVdijkn6MwqhcGm2RBsnqsxm2rMc-5GS7OpxtCiO90tWLcD-L1q10WZf9jNbXa275IdXch7rGxWSrKCfdliUFL7EyCZ7AKMDnxI4CbjY3jlI0--W62g</recordid><startdate>199708</startdate><enddate>199708</enddate><creator>Hron, P.</creator><creator>Šlechtová, J.</creator><creator>Smetana, K.</creator><creator>Dvořánková, B.</creator><creator>Lopour, P.</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>199708</creationdate><title>Silicone rubber-hydrogel composites as polymeric biomaterials: IX. Composites containing powdery polyacrylamide hydrogel</title><author>Hron, P. ; Šlechtová, J. ; Smetana, K. ; Dvořánková, B. ; Lopour, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-7a7fbf543071d0e3fcdba0532e3e57747de78a42554ca08bd8de82c7cfa754053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>3T3 Cells</topic><topic>Acrylic Resins - chemistry</topic><topic>Animals</topic><topic>Biocompatible Materials</topic><topic>Biological and medical sciences</topic><topic>Cell Adhesion</topic><topic>composite</topic><topic>Composite Resins - chemistry</topic><topic>Humans</topic><topic>hydrogel</topic><topic>Keratinocytes</topic><topic>Materials Testing</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Polyacrylamide</topic><topic>Polymers - chemistry</topic><topic>Powders</topic><topic>Prostheses and Implants</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>silicone rubber</topic><topic>Silicones - chemistry</topic><topic>Spectrophotometry, Ultraviolet</topic><topic>Technology. Biomaterials. Equipments. Material. Instrumentation</topic><topic>Tensile Strength</topic><topic>Tetrazolium Salts</topic><topic>Thiazoles</topic><topic>Water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hron, P.</creatorcontrib><creatorcontrib>Šlechtová, J.</creatorcontrib><creatorcontrib>Smetana, K.</creatorcontrib><creatorcontrib>Dvořánková, B.</creatorcontrib><creatorcontrib>Lopour, P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biomaterials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hron, P.</au><au>Šlechtová, J.</au><au>Smetana, K.</au><au>Dvořánková, B.</au><au>Lopour, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Silicone rubber-hydrogel composites as polymeric biomaterials: IX. Composites containing powdery polyacrylamide hydrogel</atitle><jtitle>Biomaterials</jtitle><addtitle>Biomaterials</addtitle><date>1997-08</date><risdate>1997</risdate><volume>18</volume><issue>15</issue><spage>1069</spage><epage>1073</epage><pages>1069-1073</pages><issn>0142-9612</issn><eissn>1878-5905</eissn><abstract>A composite material has been prepared consisting of a silicone rubber matrix and particulate lightly cross-linked polyacrylamide hydrogel. The material, resembling common silicone rubber, is hydrophilic and swells in water like hydrogels. The polyacrylamide has a high specific surface area, a relatively low content of water-soluble low-molecular-weight compounds and, owing to its nonionogenic character, a pH-independent swelling degree. For the composite material consisting of the silicone rubber and very fine powdery cross-linked polyacrylamide, we have measured the rate of swelling in water, the mechanical properties (tensile strength, break elongation, hardness, resilience), biological properties (implantation test, cytotoxicity, cell cultivation) and UV absorption of its water extracts. The polyacrylamide and polysiloxane purity, as the composite material starting components, has been determined to be satisfactory. As a result, a high swelling rate of the prepared composite material has been observed, resulting in reaching more than 70% wt of water of the equilibrium swelling. The results show that the composite material is suitable for biological and medical use.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>9239469</pmid><doi>10.1016/S0142-9612(97)00039-2</doi><tpages>5</tpages></addata></record> |
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| subjects | 3T3 Cells Acrylic Resins - chemistry Animals Biocompatible Materials Biological and medical sciences Cell Adhesion composite Composite Resins - chemistry Humans hydrogel Keratinocytes Materials Testing Medical sciences Mice Polyacrylamide Polymers - chemistry Powders Prostheses and Implants Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Rats Rats, Wistar silicone rubber Silicones - chemistry Spectrophotometry, Ultraviolet Technology. Biomaterials. Equipments. Material. Instrumentation Tensile Strength Tetrazolium Salts Thiazoles Water |
| title | Silicone rubber-hydrogel composites as polymeric biomaterials: IX. Composites containing powdery polyacrylamide hydrogel |
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