P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1

The factors determining disease severity in malaria are complex and include host polymorphisms, acquired immunity and parasite virulence. Studies in Africa have shown that severe malaria is associated with the ability of erythrocytes infected with the parasite Plasmodium falciparum to bind uninfecte...

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Veröffentlicht in:Nature (London) 1997-07, Vol.388 (6639), p.292-295
Hauptverfasser: ROWE, J. A, MOULDS, J. M, NEWBOLD, C. I, MILLER, L. H
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Sprache:eng
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