Pharmacokinetics of lisinopril (IV/PO) in healthy volunteers

When three intravenous doses of lisinopril were administered to healthy volunteers, area under the curve (to infinity) vs dose was linear with a positive intercept. Subtracting area under the extrapolated terminal phase of the serum profile from zero to infinity retained the linear relationship, but...

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Veröffentlicht in:Biopharmaceutics & drug disposition 1989-07, Vol.10 (4), p.397-409
Hauptverfasser: Beermann, Bjorn, Till, Alice E., Gomez, Hector J., Hichens, Martin, Bolognese, James A., Junggren, Inga-Lill
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Sprache:eng
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