Cellular and viral protein interactions regulating I kappa B alpha activity during human retrovirus infection

NF‐κB/Rel transcription factors participate in the activation of numerous genes involved in immune regulation/inflammation including cytokines, cell surface receptors, adhesion molecules, and acute phase proteins. NF‐κB activity is controlled by inhibitory proteins, IκBs, that maintain the DNA‐bindi...

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Veröffentlicht in:	Journal of leukocyte biology 1997-07, Vol.62 (1), p.82-92
Hauptverfasser:	Hiscott, John, Beauparlant, Pierre, Crepieux, Pascale, DeLuca, Carmela, Kwon, Hakju, Lin, Rongtuan, Petropoulos, Louisa
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Amino Acid Sequence Casein Kinase II Cell Line Cytokines - biosynthesis DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism Gene Products, tax - metabolism HIV-1 - physiology human immunodeficiency virus human immunodeficiency virus 1 human T-lymphotropic virus 1 Human T-lymphotropic virus 1 - physiology Humans I-kappa B Proteins Models, Biological Molecular Sequence Data NF-kappa B - antagonists & inhibitors NF-kappa B - physiology NF-KappaB Inhibitor alpha nuclear factor‐κB nuclear transcription factor Protein-Serine-Threonine Kinases - metabolism Receptors, Cell Surface - biosynthesis Rel Retroviridae - physiology RNA, Viral - metabolism Signal Transduction Viral Proteins - metabolism Virus Replication
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