Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration

We examined the impact of aging on the numbers of photoreceptors and retinal pigment epithelium (RPE) cells, and the number of photoreceptors per RPE cell profile, in selected regions of 30 human eyes. The mean ratio of photoreceptors to RPE cell was higher in the macula than in the paramacula (P le...

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Veröffentlicht in:	Investigative ophthalmology & visual science 1989-08, Vol.30 (8), p.1691-1699
Hauptverfasser:	Dorey, CK, Wu, G, Ebenstein, D, Garsd, A, Weiter, JJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aging - metabolism Aging - physiology Biological and medical sciences Cell Count Cell Survival Child Child, Preschool Humans Infant Infant, Newborn Lipofuscin - metabolism Macular Degeneration - metabolism Medical sciences Middle Aged Ophthalmology Phagocytosis Photoreceptor Cells - metabolism Pigment Epithelium of Eye - metabolism Pigments, Biological - metabolism Retina - metabolism Retina - physiology Retinopathies Statistics as Topic
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