Effects of propylthiouracil and methimazole on splanchnic hemodynamics in awake and unrestrained rats

The treatment of alcoholic liver disease with propylthiouracil is based on its effect of suppressing the ethanol‐induced increase in hepatic oxygen consumption. It has been postulated that liver necrosis ensues when the increase in oxygen demand by the liver exceeds oxygen delivery to this organ. Da...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1989-09, Vol.10 (3), p.273-278
Hauptverfasser:	Kawasaki, Tsunehisa, Carmichael, Frederick J., Giles, Gwynne, Saldivia, Victor, Israel, Yedy, Orrego, Hector
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Administration Schedule Ethanol - pharmacology Hemodynamics - drug effects Liver Circulation - drug effects Male Methimazole - pharmacology Propylthiouracil - pharmacology Rats Rats, Inbred Strains Thyroxine - blood Vascular Resistance - drug effects
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