Comparative chemotherapeutic activity of new fluorinated 4-quinolones and standard agents against a variety of bacteria in a mouse infection model

The new fluorinated 4-quinolones appear to represent orally effective alternatives to parenteral and oral agents currently in use. A number of new fluorinated 4-quinolones were compared in acute systemic mouse-infection models with various Gram-positive cocci (streptococci and staphylococci), Entero...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1989-05, Vol.23 (5), p.729-736
Hauptverfasser:	SESNIE, J. C, FRITSCH, P. W, GRIFFIN, T. J, HEIFETZ, C. L, LEOPOLD, E. T, MALTA, T. E, SHAPIRO, M. A, VINCENT, P. W
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Quinolones Animals Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Infections - drug therapy Bacterial Infections - microbiology Biological and medical sciences Enterobacteriaceae - drug effects In Vitro Techniques Medical sciences Mice Pharmacology. Drug treatments Pseudomonas Infections - drug therapy Pseudomonas Infections - microbiology Streptococcal Infections - drug therapy Streptococcal Infections - microbiology
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