The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain
After 21-day-old weanling rats were maintained on diets deficient in riboflavin the weights of their brains were 19.8% less than those of rats on control diets. In riboflavin deficiency, the myelin lipids, cerebrosides, and sphingomyelin, as well as phosphatidylethanolamine, a significant component...
Gespeichert in:
| Veröffentlicht in: | Journal of Nutritional Science and Vitaminology 1989, Vol.35(3), pp.193-197 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 197 |
|---|---|
| container_issue | 3 |
| container_start_page | 193 |
| container_title | Journal of Nutritional Science and Vitaminology |
| container_volume | 35 |
| creator | Ogunleye, A.J. (University of Ilorin (Nigeria)) Odutuga, A.A |
| description | After 21-day-old weanling rats were maintained on diets deficient in riboflavin the weights of their brains were 19.8% less than those of rats on control diets. In riboflavin deficiency, the myelin lipids, cerebrosides, and sphingomyelin, as well as phosphatidylethanolamine, a significant component of the myelin membrane, were considerably reduced in proportion. It is considered that riboflavin plays some role in the metabolism of essential fatty acids in brain lipids and the pathological effect of its deficiency is similar to that of essential fatty acid deficiency, causing a fast impairment to brain development and maturation. |
| doi_str_mv | 10.3177/jnsv.35.193 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79131364</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79131364</sourcerecordid><originalsourceid>FETCH-LOGICAL-c524t-15a0834554109e1ab9608aad19f39213fda48eb9be64fbe45b37d6f67b3659b33</originalsourceid><addsrcrecordid>eNo9kM1rGzEQxUVpSZ20p9wKAZ16CetqLO1qdSxpPgm0hyRXIWlHjsxa60hrQ_77ylnjywyP9-bH8Ag5BzbnIOWvVcy7Oa_noPgnMoO2hUpKsfhMZowzqETL2FdymvOKMaFa0Z6Qk4VsWKNgRl6eXpGi9-hGOniagh18b3Yh0g59cAGje6dDpA4T2rRdUxO7SWDfF1luOtxhP2xCXNJkRmqTCfEb-eJNn_H7YZ-R55vrp6u76vHv7f3V78fK1QsxVlAb1nJR1wKYQjBWNaw1pgPluVoA950RLVplsRHeoqgtl13jG2l5UyvL-Rn5OXE3aXjbYh71OmRXXjMRh23WUgEH3ogSvJyCLg05J_R6k8LapHcNTO9b1PsWNa91abGkLw7YrV1jd8weaiv-n8lf5dEs8eibNAbX4wcLlOR73mEU7NF2ryZpjAXzY8J4M2izTCHrh39KMGAC-H_Pvo51</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79131364</pqid></control><display><type>article</type><title>The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese</source><creator>Ogunleye, A.J. (University of Ilorin (Nigeria)) ; Odutuga, A.A</creator><creatorcontrib>Ogunleye, A.J. (University of Ilorin (Nigeria)) ; Odutuga, A.A</creatorcontrib><description>After 21-day-old weanling rats were maintained on diets deficient in riboflavin the weights of their brains were 19.8% less than those of rats on control diets. In riboflavin deficiency, the myelin lipids, cerebrosides, and sphingomyelin, as well as phosphatidylethanolamine, a significant component of the myelin membrane, were considerably reduced in proportion. It is considered that riboflavin plays some role in the metabolism of essential fatty acids in brain lipids and the pathological effect of its deficiency is similar to that of essential fatty acid deficiency, causing a fast impairment to brain development and maturation.</description><identifier>ISSN: 0301-4800</identifier><identifier>EISSN: 1881-7742</identifier><identifier>DOI: 10.3177/jnsv.35.193</identifier><identifier>PMID: 2760691</identifier><language>eng</language><publisher>Japan: Center for Academic Publications Japan</publisher><subject>Animals ; Body Weight ; BRAIN ; Brain - growth & development ; Brain - metabolism ; brain and development ; CARENCE EN VITAMINE ; Cerebellum - growth & development ; Cerebellum - metabolism ; CEREBRO ; DEFICIENCIA DE VITAMINAS ; deficiency ; ENCEPHALE ; Lipid Metabolism ; lipids ; Male ; Organ Size ; RAT ; RATA ; RATS ; Rats, Inbred Strains ; RIBOFLAVIN ; Riboflavin Deficiency - metabolism ; Riboflavin Deficiency - physiopathology ; RIBOFLAVINA ; RIBOFLAVINE ; VITAMIN DEFICIENCIES</subject><ispartof>Journal of Nutritional Science and Vitaminology, 1989, Vol.35(3), pp.193-197</ispartof><rights>the Center for Academic Publications Japan</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-15a0834554109e1ab9608aad19f39213fda48eb9be64fbe45b37d6f67b3659b33</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,1877,4010,27904,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2760691$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ogunleye, A.J. (University of Ilorin (Nigeria))</creatorcontrib><creatorcontrib>Odutuga, A.A</creatorcontrib><title>The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain</title><title>Journal of Nutritional Science and Vitaminology</title><addtitle>J Nutr Sci Vitaminol</addtitle><description>After 21-day-old weanling rats were maintained on diets deficient in riboflavin the weights of their brains were 19.8% less than those of rats on control diets. In riboflavin deficiency, the myelin lipids, cerebrosides, and sphingomyelin, as well as phosphatidylethanolamine, a significant component of the myelin membrane, were considerably reduced in proportion. It is considered that riboflavin plays some role in the metabolism of essential fatty acids in brain lipids and the pathological effect of its deficiency is similar to that of essential fatty acid deficiency, causing a fast impairment to brain development and maturation.</description><subject>Animals</subject><subject>Body Weight</subject><subject>BRAIN</subject><subject>Brain - growth & development</subject><subject>Brain - metabolism</subject><subject>brain and development</subject><subject>CARENCE EN VITAMINE</subject><subject>Cerebellum - growth & development</subject><subject>Cerebellum - metabolism</subject><subject>CEREBRO</subject><subject>DEFICIENCIA DE VITAMINAS</subject><subject>deficiency</subject><subject>ENCEPHALE</subject><subject>Lipid Metabolism</subject><subject>lipids</subject><subject>Male</subject><subject>Organ Size</subject><subject>RAT</subject><subject>RATA</subject><subject>RATS</subject><subject>Rats, Inbred Strains</subject><subject>RIBOFLAVIN</subject><subject>Riboflavin Deficiency - metabolism</subject><subject>Riboflavin Deficiency - physiopathology</subject><subject>RIBOFLAVINA</subject><subject>RIBOFLAVINE</subject><subject>VITAMIN DEFICIENCIES</subject><issn>0301-4800</issn><issn>1881-7742</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM1rGzEQxUVpSZ20p9wKAZ16CetqLO1qdSxpPgm0hyRXIWlHjsxa60hrQ_77ylnjywyP9-bH8Ag5BzbnIOWvVcy7Oa_noPgnMoO2hUpKsfhMZowzqETL2FdymvOKMaFa0Z6Qk4VsWKNgRl6eXpGi9-hGOniagh18b3Yh0g59cAGje6dDpA4T2rRdUxO7SWDfF1luOtxhP2xCXNJkRmqTCfEb-eJNn_H7YZ-R55vrp6u76vHv7f3V78fK1QsxVlAb1nJR1wKYQjBWNaw1pgPluVoA950RLVplsRHeoqgtl13jG2l5UyvL-Rn5OXE3aXjbYh71OmRXXjMRh23WUgEH3ogSvJyCLg05J_R6k8LapHcNTO9b1PsWNa91abGkLw7YrV1jd8weaiv-n8lf5dEs8eibNAbX4wcLlOR73mEU7NF2ryZpjAXzY8J4M2izTCHrh39KMGAC-H_Pvo51</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Ogunleye, A.J. (University of Ilorin (Nigeria))</creator><creator>Odutuga, A.A</creator><general>Center for Academic Publications Japan</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain</title><author>Ogunleye, A.J. (University of Ilorin (Nigeria)) ; Odutuga, A.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-15a0834554109e1ab9608aad19f39213fda48eb9be64fbe45b37d6f67b3659b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Body Weight</topic><topic>BRAIN</topic><topic>Brain - growth & development</topic><topic>Brain - metabolism</topic><topic>brain and development</topic><topic>CARENCE EN VITAMINE</topic><topic>Cerebellum - growth & development</topic><topic>Cerebellum - metabolism</topic><topic>CEREBRO</topic><topic>DEFICIENCIA DE VITAMINAS</topic><topic>deficiency</topic><topic>ENCEPHALE</topic><topic>Lipid Metabolism</topic><topic>lipids</topic><topic>Male</topic><topic>Organ Size</topic><topic>RAT</topic><topic>RATA</topic><topic>RATS</topic><topic>Rats, Inbred Strains</topic><topic>RIBOFLAVIN</topic><topic>Riboflavin Deficiency - metabolism</topic><topic>Riboflavin Deficiency - physiopathology</topic><topic>RIBOFLAVINA</topic><topic>RIBOFLAVINE</topic><topic>VITAMIN DEFICIENCIES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ogunleye, A.J. (University of Ilorin (Nigeria))</creatorcontrib><creatorcontrib>Odutuga, A.A</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Nutritional Science and Vitaminology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ogunleye, A.J. (University of Ilorin (Nigeria))</au><au>Odutuga, A.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain</atitle><jtitle>Journal of Nutritional Science and Vitaminology</jtitle><addtitle>J Nutr Sci Vitaminol</addtitle><date>1989</date><risdate>1989</risdate><volume>35</volume><issue>3</issue><spage>193</spage><epage>197</epage><pages>193-197</pages><issn>0301-4800</issn><eissn>1881-7742</eissn><abstract>After 21-day-old weanling rats were maintained on diets deficient in riboflavin the weights of their brains were 19.8% less than those of rats on control diets. In riboflavin deficiency, the myelin lipids, cerebrosides, and sphingomyelin, as well as phosphatidylethanolamine, a significant component of the myelin membrane, were considerably reduced in proportion. It is considered that riboflavin plays some role in the metabolism of essential fatty acids in brain lipids and the pathological effect of its deficiency is similar to that of essential fatty acid deficiency, causing a fast impairment to brain development and maturation.</abstract><cop>Japan</cop><pub>Center for Academic Publications Japan</pub><pmid>2760691</pmid><doi>10.3177/jnsv.35.193</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0301-4800 |
| ispartof | Journal of Nutritional Science and Vitaminology, 1989, Vol.35(3), pp.193-197 |
| issn | 0301-4800 1881-7742 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79131364 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Animals Body Weight BRAIN Brain - growth & development Brain - metabolism brain and development CARENCE EN VITAMINE Cerebellum - growth & development Cerebellum - metabolism CEREBRO DEFICIENCIA DE VITAMINAS deficiency ENCEPHALE Lipid Metabolism lipids Male Organ Size RAT RATA RATS Rats, Inbred Strains RIBOFLAVIN Riboflavin Deficiency - metabolism Riboflavin Deficiency - physiopathology RIBOFLAVINA RIBOFLAVINE VITAMIN DEFICIENCIES |
| title | The effect of riboflavin deficiency on cerebrum and cerebellum of developing rat brain |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T07%3A57%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20effect%20of%20riboflavin%20deficiency%20on%20cerebrum%20and%20cerebellum%20of%20developing%20rat%20brain&rft.jtitle=Journal%20of%20Nutritional%20Science%20and%20Vitaminology&rft.au=Ogunleye,%20A.J.%20(University%20of%20Ilorin%20(Nigeria))&rft.date=1989&rft.volume=35&rft.issue=3&rft.spage=193&rft.epage=197&rft.pages=193-197&rft.issn=0301-4800&rft.eissn=1881-7742&rft_id=info:doi/10.3177/jnsv.35.193&rft_dat=%3Cproquest_cross%3E79131364%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79131364&rft_id=info:pmid/2760691&rfr_iscdi=true |