Synaptic vesicle ceramide kinase. A calcium-stimulated lipid kinase that co-purifies with brain synaptic vesicles

Much current work on the mechanism of neurosecretion has focused on proteins specific to neural secretory vesicles (synaptic vesicles). We report a calcium-stimulated lipid kinase that co-purifies with rat brain synaptic vesicles. This enzyme activity is found only in membrane fractions that contain...

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Veröffentlicht in:	The Journal of biological chemistry 1989-08, Vol.264 (24), p.14354-14360
Hauptverfasser:	BAJJALIEH, S. M, MARTIN, T. F. J, FLOOR, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Biomarkers brain Brain - enzymology Calcium - physiology Cytoplasm - enzymology Cytoplasm - physiology Diacylglycerol Kinase Enzyme Activation Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Kinetics Phosphorylation Phosphotransferases - isolation & purification Phosphotransferases - metabolism Rats Substrate Specificity synaptic vesicles Synaptic Vesicles - enzymology Transferases
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