In vitro spinal cord conduction block during exposure to a xanthine oxidase/hypoxanthine system: noninvolvement of superoxide and hydrogen peroxide

The effects of a reactive oxygen system on axonal conduction were assessed in an in vitro rat spinal cord preparation. An enzyme system, containing hypoxanthine and xanthine oxidase as a source of superoxide and hydrogen peroxide, was used in combination with ADP and FeCl3 as catalysts for peroxidat...

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