Substrate specificity and affinity of a protein modulated by bound water molecules

WATER molecules influence molecular interactions in all biological systems, yet it is extremely difficult to understand their effects in precise atomic detail. Here we present evidence, based on highly refined atomic structures of the complexes of the L-arabinose-binding protein with L-arabinose, D-...

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Veröffentlicht in:Nature (London) 1989-08, Vol.340 (6232), p.404-407
Hauptverfasser: Quiocho, F. A, Wilson, D. K, Vyas, N. K
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Sprache:eng
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