In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer

The antibacterial activity of trovafloxacin was compared with that of ciprofloxacin, levofloxacin, ofloxacin, sparfloxacin and norfloxacin against bacterial isolates from patients with cancer. In general, the activity of trovafloxacin was comparable to that of ciprofloxacin, levofloxacin and sparflo...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1997-06, Vol.39 Suppl B (suppl 2), p.15-22
Hauptverfasser:	Rolston, K V, Ho, D H, LeBlanc, B, Streeter, H, Dvorak, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - pharmacology Ciprofloxacin - pharmacology Fluoroquinolones Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans Levofloxacin Microbial Sensitivity Tests Naphthyridines - pharmacology Neoplasms - microbiology Norfloxacin - pharmacology Ofloxacin - pharmacology Quinolones - pharmacology
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Zusammenfassung:	The antibacterial activity of trovafloxacin was compared with that of ciprofloxacin, levofloxacin, ofloxacin, sparfloxacin and norfloxacin against bacterial isolates from patients with cancer. In general, the activity of trovafloxacin was comparable to that of ciprofloxacin, levofloxacin and sparfloxacin against most Gram-negative isolates tested (minor differences in the activity of each agent against individual species were seen) and it was the most active agent tested against Stenotrophomonas maltophilia, inhibiting 80% of these isolates at
ISSN:	0305-7453 1460-2091
DOI:	10.1093/jac/39.suppl_2.15