Rapid Human Chromosome Aberration Analysis Using Fluorescence in Situ Hybridization

Summary We have used in situ hybridization of repeat-sequence DNA probes, specific to the paracentromeric locus 1q12 and the telomeric locus 1p36, to fluorescently stain regions that flank human chromosome 1p. This procedure was used for fast detection of structural aberrations involving human chrom...

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Veröffentlicht in:	International journal of radiation biology 1989, Vol.56 (1), p.35-44
Hauptverfasser:	Lucas, J.N., Tenjin, T., Straume, T., Pinkel, D., Moore II, D., Litt, M., Gray, J.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cesium Radioisotopes Chromosome Aberrations Chromosomes, Human, Pair 1 - radiation effects Cobalt Radioisotopes Fluorescence gamma radiation Gamma Rays Humans Lymphocytes - radiation effects Nucleic Acid Hybridization risk assessment Space life sciences Time Factors Translocation, Genetic
Online-Zugang:	Volltext
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