In vitro evidence for a neurite growth‐promoting activity in trembler mouse serum

Basal lamina components, such as heparan sulfate proteoglycan (HSPG) and laminin play an important role in neuritic outgrowth for CNS and PNS neurons in culture. The mutant mouse ‘Trembler’ is characterized by hypomyelinization and production of an excess of basal lamina layers around Schwann cells...

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Veröffentlicht in:	International journal of developmental neuroscience 1989, Vol.7 (3), p.281-294
Hauptverfasser:	Koenig, J., Hantaz‐Ambroise, Dj, De La Porte, S., Thi, N. A. Do, Bourre, J. M., La Chapelle, F., Koenig, H. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Chondroitin Sulfate Proteoglycans - immunology Chondroitin Sulfate Proteoglycans - physiology Dendrites - drug effects Dendrites - physiology Extracellular matrix Floxuridine - pharmacology Fundamental and applied biological sciences. Psychology Glycosaminoglycans - physiology Heparan Sulfate Proteoglycans Heparitin Sulfate - immunology Heparitin Sulfate - physiology Immune Sera In Vitro Techniques Isolated neuron and nerve. Neuroglia Laminin - immunology Laminin - physiology Mice Mice, Neurologic Mutants - metabolism Mitogenic factors Nerve Growth Factors - blood Nerve Growth Factors - pharmacology Neuritic outgrowth Proteoglycans - physiology Schwann cell mutation Serum Spinal Cord - cytology Spinal Cord - drug effects Vertebrates: nervous system and sense organs
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