Effect of carbon dioxide on cerebral metabolism during hypoxia-ischemia in the immature rat

We previously have demonstrated that hypocapnia aggravates and hypercapnia protects the immature rat from hypoxic-ischemic brain damage. To ascertain cerebral blood flow (CBF) and metabolic correlates, 7-d postnatal rats were subjected to hypoxia-ischemia during which they were rendered either hypo-...

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Veröffentlicht in:	Pediatric research 1997-07, Vol.42 (1), p.24-29
Hauptverfasser:	VANNUCCI, R. C, BRUCKLACHER, R. M, VANNUCCI, S. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Brain - metabolism Brain Injuries - prevention & control Brain Ischemia - complications Brain Ischemia - metabolism Carbon Dioxide - metabolism Cerebrovascular Circulation Citric Acid Cycle Emergency and intensive care: neonates and children. Prematurity. Sudden death Glucose - metabolism Glutamic Acid - cerebrospinal fluid Glycolysis Hydrogen-Ion Concentration Hypercapnia - complications Hypercapnia - metabolism Hypocapnia - complications Hypocapnia - metabolism Hypoxia, Brain - complications Hypoxia, Brain - metabolism Intensive care medicine Medical sciences Phosphates - metabolism Rats Rats, Sprague-Dawley
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