TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis

The anaphylatoxin C5a has been implicated in the pathogenesis of bacterial meningitis as a potent mediator of inflammation in the subarachnoid space. We investigated the expression of the receptor for C5a (C5aR) in brains of mice with experimental Listeria monocytogenes (LM) meningoencephalitis. In...

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Veröffentlicht in:	The Journal of immunology (1950) 1997-07, Vol.159 (2), p.861-869
Hauptverfasser:	Stahel, PF, Frei, K, Eugster, HP, Fontana, A, Hummel, KM, Wetsel, RA, Ames, RS, Barnum, SR
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - biosynthesis Female Humans Immunohistochemistry Listeria monocytogenes Listeriosis - immunology Listeriosis - metabolism Meningoencephalitis - immunology Meningoencephalitis - metabolism Mice Mice, Inbred ICR Neurons - immunology Neurons - metabolism Receptor, Anaphylatoxin C5a Receptors, Complement - biosynthesis RNA, Messenger - analysis Tumor Necrosis Factor-alpha - metabolism Tumor Necrosis Factor-alpha - pharmacology
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