DNA Mismatch Correction in a Defined System

DNA mismatch correction is a strand-specific process involving recognition of noncomplementary Watson-Crick nucleotide pairs and participation of widely separated DNA sites. The Escherichia coli methyl-directed reaction has been reconstituted in a purified system consisting of MutH, MutL, and MutS p...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1989-07, Vol.245 (4914), p.160-164
Hauptverfasser:	Lahue, R. S., Au, K. G., Modrich, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biochemistry Biological and medical sciences Biosynthesis Circles Complementary DNA Correctional system DNA DNA mismatch repair DNA Repair DNA, Bacterial - biosynthesis DNA, Bacterial - genetics Enzymes Escherichia coli Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Genetic mutation Genetics Methylation Molecular and cellular biology Molecular genetics Molecules Mutagenesis. Repair Mutation Nucleotide sequence Proteins
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