Chlormethiazole: neurochemical actions at the γ-aminobutyric acid receptor complex

Chlormethiazole has been extensively employed as a sedative/hypnotic and anticonvulsant for more than 25 years. While pharmacological and electrophysiological studies have implicated the GABA A receptor complex in these actions, neurochemical findings have not been consistent with this conclusion. W...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmacology 1989-05, Vol.164 (1), p.153-158
Hauptverfasser:	Moody, Eric J., Skolnick, Phil
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzodiazepines Binding, Competitive - drug effects Biological and medical sciences Brain Chemistry - drug effects Chlormethiazole Chlormethiazole - pharmacology Cl − uptake Flunitrazepam - metabolism Hypnotics. Sedatives In Vitro Techniques Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Receptors, GABA-A - metabolism Sulfur Radioisotopes Synaptoneurosomes Synaptosomes - drug effects Synaptosomes - metabolism t-Butylbicyclophosphorothionate γ-Aminobutyric acid (GABA)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!