Platelet adherence and thrombus formation with flowing human blood on atherosclerotic plaque: Reduced thrombogenicity of watanabe-heritable hyperlipidemic rabbit aortic subendothelium

Platelet adherence and aggregation are important in the development of ischemic sequelae in atherosclerosis. To directly examine platelet interaction with plaque, everted, deendothelialized aortic fibrous plaques from Watanabe-heritable hyperlipidemic rabbits were exposed to flowing human blood in a...

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Veröffentlicht in:	Thrombosis research 1989-04, Vol.54 (2), p.99-114
Hauptverfasser:	Lawrence, Jeffry B., Prevosti, Louis G., Kramer, Wendy S., Lu, David Y., Leon, Martin B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - analysis Aorta - ultrastructure Arteriosclerosis - complications Arteriosclerosis - physiopathology atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood Platelets - physiology Blood Platelets - ultrastructure Cardiology. Vascular system Endothelium, Vascular Medical sciences Microscopy, Electron Perfusion - methods platelet adherence Platelet Adhesiveness platelet spreading Platelets Rabbits Regional Blood Flow surface thrombogenicity thrombosis Thrombosis - etiology Thrombosis - physiopathology
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