Transducin GTPase provides for rapid quenching of the cGMP cascade in rod outer segments

The role of transducin GTPase in rapid cGMP phosphodiesterase quenching was studied by simultaneous registration of GTP hydrolysis and phosphodiesterase activity in the same rod outer segments (ROS) preparation. The results thus obtained allow the conclusion that: (i) phosphodiesterase quenching coi...

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Veröffentlicht in:	FEBS letters 1989-07, Vol.250 (2), p.353-356
Hauptverfasser:	Arshavsky, V.Yu, Antoch, M.P., Lukjanov, K.A., Philippov, P.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals AppNHp, adenylyl imidodiphosphate Biological and medical sciences Cattle Cell physiology Cyclic GMP - metabolism Fundamental and applied biological sciences. Psychology GTP Phosphohydrolases - metabolism Hydrolysis Molecular and cellular biology Mops, morpholinepropane-sulfonic acid PDE, cyclic GMP phosphodiesterase Phosphodiesterase Phosphoric Diester Hydrolases - metabolism Phosphoric Monoester Hydrolases - metabolism Photoreception Photoreceptor Cells - metabolism Rod Cell Outer Segment - enzymology Rod Cell Outer Segment - metabolism ROS, rod outer segments Signal quenching T, transducin Transducin - metabolism Transducin GTPase Vision, photoreception
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