A novel explanation for fluctuations of ion current through narrow pores

Fluctuation of ion current, between a high conductance and a low conductance state, through biological ion channels and pores is assumed to arise from conformational changes between an “open” and a “closed” configuration. Here we offer an additional mechanism that arises from changes in ionization o...

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Veröffentlicht in:	The FASEB journal 1997-06, Vol.11 (7), p.600-608
Hauptverfasser:	Korchev, Y. E., Bashford, C. L., Alder, G. M., Apel, P. Y., Edmonds, D. T., Lev, A. A., Nandi, K., Zima, A. V., Pasternak, C. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Toxins - pharmacology Electric Conductivity Hemolysin Proteins - pharmacology Ion Channels - drug effects Ion Channels - metabolism Ions Membranes, Artificial PETP membrane Polyethylene Terephthalates Staphylococcus aureus α toxin channel
Online-Zugang:	Volltext
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