S‐Adenosylmethionine Decarboxylase Activity Is Decreased in the Rat Cortex After Traumatic Brain Injury

: S‐Adenosyl‐l‐methionine decarboxylase (SAMdc) and l‐ornithine decarboxylase (ODC) are major enzymes regulating polyamine synthesis. Following ischemia, putrescine content increases as a result of post‐traumatic activation of ODC and inhibition of SAMdc. These alterations are thought to mediate ede...

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Veröffentlicht in:	Journal of neurochemistry 1997-07, Vol.69 (1), p.259-265
Hauptverfasser:	Henley, Charles M., Wey, Karen, Takashima, Amy, Mills, Charles, Granmayeh, Elaine, Krishnappa, Indra, Robertson, Claudia S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosylmethionine Decarboxylase - metabolism Animals Biological and medical sciences Brain Edema - metabolism Brain Injuries - metabolism Brain injury Cerebral Cortex - enzymology Edema Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Polyamines Rats Rats, Inbred Strains S‐Adenosylmethionine decarboxylase Trauma Traumas. Diseases due to physical agents Wounds and Injuries - metabolism
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