Endothelin-1 and endothelin-4 stimulate monocyte production of cytokines

OBJECTIVE To determine the effect of endothelin-1 and endothelin-4 on human monocyte production of cytokines. DESIGN Previous work from our laboratory has shown that endothelin-1 activates leukocytes. Endothelin-1 and endothelin-3 are principally produced by vascular endothelium. However, epidermal...

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Veröffentlicht in:	Critical care medicine 1997-06, Vol.25 (6), p.958-964
Hauptverfasser:	Cunningham, Michael E, Huribal, Marsel, Bala, R. J, McMillen, Marvin A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cells, Cultured Dose-Response Relationship, Drug Endothelin-1 - pharmacology Endothelin-1 - physiology Endothelins - pharmacology Endothelins - physiology Female Fundamental and applied biological sciences. Psychology Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis Humans Inflammation Interleukin-6 - biosynthesis Interleukin-8 - biosynthesis Interleukins - biosynthesis Male Molecular and cellular biology Monocytes - metabolism Tumor Necrosis Factor-alpha - biosynthesis
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