Co-stimulation in T cell responses

Antigen-specific T cell responses have primarily been considered in terms of activation signals delivered through the TCR and the co-stimulatory molecule CD28. In the past few years, studies have demonstrated the critical importance of inhibitory signals for regulating lymphocyte activation. CD28 an...

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Veröffentlicht in:	Current opinion in immunology 1997-06, Vol.9 (3), p.396-404
Hauptverfasser:	Chambers, Cynthia A, Allison, James P
Format:	Artikel
Sprache:	eng
Schlagworte:	Abatacept Animals Antigens, CD Antigens, Differentiation - immunology CD28 Antigens - immunology CTLA-4 Antigen Humans Immunoconjugates Lymphocyte Activation - immunology Signal Transduction - immunology T-Lymphocytes - immunology
Online-Zugang:	Volltext
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