Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes

Treatment of rabbits with a variety of dissimilar chemicals, including ethanol, acetone, and imidazole, results in elevated levels of hepatic and renal cytochrome P-450 form 3a, also designated P-450ALC or P-450IIE. The P450IIE1 subfamily in rabbits is composed of two genes that encode proteins with...

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Veröffentlicht in:	Molecular pharmacology 1989-07, Vol.36 (1), p.61-65
Hauptverfasser:	PORTER, T. D, KHANI, S. C, COON, M. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cytochrome P-450 Enzyme System - genetics Enzyme Induction - drug effects Ethanol - pharmacology Female Fundamental and applied biological sciences. Psychology Gene expression Isoenzymes - genetics Male Molecular and cellular biology Molecular genetics Organ Specificity Rabbits RNA, Messenger - analysis Sex Factors Transcription, Genetic
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