Leukocytes and decreased left-ventricular contractility during endotoxemia in rabbits

We hypothesized that leukocytes contribute to decreased myocardial contractility following endotoxin infusion. To test this hypothesis, we administered endotoxin (1 mg/kg intravenously) to intact, anesthetized rabbits whose arterial blood perfused two isolated hearts at a constant pressure (75 mm Hg...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1997-06, Vol.155 (6), p.1977-1983
Hauptverfasser:	GRANTON, J. T, GODDARD, C. M, ALLARD, M. F, VAN EEDEN, S, WALLEY, K. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Emergency and intensive care: infection, septic shock Endotoxemia - blood Endotoxemia - pathology Endotoxemia - physiopathology Female In Vitro Techniques Intensive care medicine Leukocyte Count Leukocytes - physiology Medical sciences Myocardial Contraction Neutrophils - pathology Perfusion Rabbits Ventricular Function, Left
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