Laser treatment for further depigmentation in vitiligo
Background In patients with vitiligo, sometimes the greatest part of the skin has already lost its melanocytes. The remaining pigmented patches can be removed by using strong bleaching creams, but many adverse events have been reported with this treatment. Anew depigmentation therapy could be treatm...
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| Veröffentlicht in: | International journal of dermatology 1997-05, Vol.36 (5), p.386-388 |
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| container_title | International journal of dermatology |
| container_volume | 36 |
| creator | Thissen, Monique Westerhof, Wiete |
| description | Background
In patients with vitiligo, sometimes the greatest part of the skin has already lost its melanocytes. The remaining pigmented patches can be removed by using strong bleaching creams, but many adverse events have been reported with this treatment. Anew depigmentation therapy could be treatment with a Ruby laser.
Methods
Before treatment, the patients filled out a questionnaire about their vitiligo history. Eight patients with remaining pigmentation of the arms, hands, and face were treated once with a Ruby laser. Patients were monitored for developing repigmentation during the 9 months after treatment.
Results
In patients with a positive Koebner phenomenon, a permanent state of depigmentation was reached after laser therapy. None of the treated patients showed severe side‐effects.
Conclusions
Ruby laser treatment can be an effective, fast, and safe method for removing cosmetically disturbing remnants of normal pigmentation in vitiligo patients with a positive Koebner phenomenon. |
| doi_str_mv | 10.1046/j.1365-4362.1997.00144.x |
| format | Article |
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In patients with vitiligo, sometimes the greatest part of the skin has already lost its melanocytes. The remaining pigmented patches can be removed by using strong bleaching creams, but many adverse events have been reported with this treatment. Anew depigmentation therapy could be treatment with a Ruby laser.
Methods
Before treatment, the patients filled out a questionnaire about their vitiligo history. Eight patients with remaining pigmentation of the arms, hands, and face were treated once with a Ruby laser. Patients were monitored for developing repigmentation during the 9 months after treatment.
Results
In patients with a positive Koebner phenomenon, a permanent state of depigmentation was reached after laser therapy. None of the treated patients showed severe side‐effects.
Conclusions
Ruby laser treatment can be an effective, fast, and safe method for removing cosmetically disturbing remnants of normal pigmentation in vitiligo patients with a positive Koebner phenomenon.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1046/j.1365-4362.1997.00144.x</identifier><identifier>PMID: 9199992</identifier><identifier>CODEN: IJDEBB</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Child ; Dermatology ; Female ; Humans ; Laser Therapy ; Male ; Medical sciences ; Melanocytes - physiology ; Melanocytes - radiation effects ; Middle Aged ; Pigmentary diseases of the skin ; Pigmentation - physiology ; Pigmentation - radiation effects ; Treatment Outcome ; Vitiligo - physiopathology ; Vitiligo - radiotherapy</subject><ispartof>International journal of dermatology, 1997-05, Vol.36 (5), p.386-388</ispartof><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5466-373f6ce90564504dbec377e544ececab1c6f0d688ffde0f560ae162cb8b258703</citedby><cites>FETCH-LOGICAL-c5466-373f6ce90564504dbec377e544ececab1c6f0d688ffde0f560ae162cb8b258703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1365-4362.1997.00144.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1365-4362.1997.00144.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2701425$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9199992$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thissen, Monique</creatorcontrib><creatorcontrib>Westerhof, Wiete</creatorcontrib><title>Laser treatment for further depigmentation in vitiligo</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Background
In patients with vitiligo, sometimes the greatest part of the skin has already lost its melanocytes. The remaining pigmented patches can be removed by using strong bleaching creams, but many adverse events have been reported with this treatment. Anew depigmentation therapy could be treatment with a Ruby laser.
Methods
Before treatment, the patients filled out a questionnaire about their vitiligo history. Eight patients with remaining pigmentation of the arms, hands, and face were treated once with a Ruby laser. Patients were monitored for developing repigmentation during the 9 months after treatment.
Results
In patients with a positive Koebner phenomenon, a permanent state of depigmentation was reached after laser therapy. None of the treated patients showed severe side‐effects.
Conclusions
Ruby laser treatment can be an effective, fast, and safe method for removing cosmetically disturbing remnants of normal pigmentation in vitiligo patients with a positive Koebner phenomenon.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Dermatology</subject><subject>Female</subject><subject>Humans</subject><subject>Laser Therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanocytes - physiology</subject><subject>Melanocytes - radiation effects</subject><subject>Middle Aged</subject><subject>Pigmentary diseases of the skin</subject><subject>Pigmentation - physiology</subject><subject>Pigmentation - radiation effects</subject><subject>Treatment Outcome</subject><subject>Vitiligo - physiopathology</subject><subject>Vitiligo - radiotherapy</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMlu2zAQhomiQeK6fYQCOhS9SeVOCeilyNYETnpxkiNBUcOUjiw5pJw6bx8qMnzuieC_zAw-hDKCC4K5_LEqCJMi50zSglSVKjAmnBe7D2g2GZLRj2iWVJJXWFQn6FOMq_RllPBjdFylUlXRGZILEyFkQwAzrKEbMteHzG3D8DepDWz846iawfdd5rvsxQ--9Y_9Z3TkTBvhy_6do7uL8-Xp73zx5_Lq9Ncit4JLmTPFnLSQLpBcYN7UYJlSIDgHC9bUxEqHG1mWzjWAnZDYAJHU1mVNRakwm6Pv09xN6J-3EAe99tFC25oO-m3UqsIlw5imYDkFbehjDOD0Jvi1Ca-aYD0i0ys9ktEjMj0i0-_I9C5Vv-53bOs1NIfinlHyv-19E61pXTCd9fEQoyrNoSLFfk6xf76F1_9er6-uz1gpUz2f6j4OsDvUTXjSUjEl9MPtpWY3lHG5vNcL9gaLfJWh</recordid><startdate>199705</startdate><enddate>199705</enddate><creator>Thissen, Monique</creator><creator>Westerhof, Wiete</creator><general>Blackwell Publishing Ltd</general><general>Blackwell Science</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199705</creationdate><title>Laser treatment for further depigmentation in vitiligo</title><author>Thissen, Monique ; Westerhof, Wiete</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5466-373f6ce90564504dbec377e544ececab1c6f0d688ffde0f560ae162cb8b258703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Dermatology</topic><topic>Female</topic><topic>Humans</topic><topic>Laser Therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanocytes - physiology</topic><topic>Melanocytes - radiation effects</topic><topic>Middle Aged</topic><topic>Pigmentary diseases of the skin</topic><topic>Pigmentation - physiology</topic><topic>Pigmentation - radiation effects</topic><topic>Treatment Outcome</topic><topic>Vitiligo - physiopathology</topic><topic>Vitiligo - radiotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thissen, Monique</creatorcontrib><creatorcontrib>Westerhof, Wiete</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thissen, Monique</au><au>Westerhof, Wiete</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laser treatment for further depigmentation in vitiligo</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>1997-05</date><risdate>1997</risdate><volume>36</volume><issue>5</issue><spage>386</spage><epage>388</epage><pages>386-388</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><coden>IJDEBB</coden><abstract>Background
In patients with vitiligo, sometimes the greatest part of the skin has already lost its melanocytes. The remaining pigmented patches can be removed by using strong bleaching creams, but many adverse events have been reported with this treatment. Anew depigmentation therapy could be treatment with a Ruby laser.
Methods
Before treatment, the patients filled out a questionnaire about their vitiligo history. Eight patients with remaining pigmentation of the arms, hands, and face were treated once with a Ruby laser. Patients were monitored for developing repigmentation during the 9 months after treatment.
Results
In patients with a positive Koebner phenomenon, a permanent state of depigmentation was reached after laser therapy. None of the treated patients showed severe side‐effects.
Conclusions
Ruby laser treatment can be an effective, fast, and safe method for removing cosmetically disturbing remnants of normal pigmentation in vitiligo patients with a positive Koebner phenomenon.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>9199992</pmid><doi>10.1046/j.1365-4362.1997.00144.x</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | International journal of dermatology, 1997-05, Vol.36 (5), p.386-388 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adolescent Adult Aged Biological and medical sciences Child Dermatology Female Humans Laser Therapy Male Medical sciences Melanocytes - physiology Melanocytes - radiation effects Middle Aged Pigmentary diseases of the skin Pigmentation - physiology Pigmentation - radiation effects Treatment Outcome Vitiligo - physiopathology Vitiligo - radiotherapy |
| title | Laser treatment for further depigmentation in vitiligo |
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