The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila

During animal development cellular differentiation is often preceded by an asymmetric cell division whose polarity is determined by the orientation of the mitotic spindle. In the fruit fly, Drosophila melanogaster, the oocyte differentiates in a 16-cell syncytium that arises from a cystoblast which...

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Veröffentlicht in:	Development (Cambridge) 1997-06, Vol.124 (12), p.2409-2419
Hauptverfasser:	McGrail, M, Hays, T S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Cell Division - genetics Cell Polarity Cytoplasm - physiology Drosophila melanogaster Drosophila melanogaster - genetics Dyneins - physiology Female Germ Cells - physiology Microtubules - physiology Mutation Oocytes - physiology Spindle Apparatus - genetics
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